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- W2011644566 abstract "A substance resembling luteinizing hormone-releasing hormone (LRF) has previously been demonstrated in preganglionic elements of the bullfrog, where it is released upon nerve stimulation and produces a slow excitatory post-synaptic potential (slow EPSP) of the principal ganglion cells (1). This LRF-like immunoreactive substance (IR-LRF) has been characterized immunologically employing several antisera specific for LRF and by high-pressure liquid chromatography (HPLC). The IR-LRF of the sympathetic ganglia is recognized by LRF antiserum R-42 but not by several other LRF antisera (IJ-29, 185 and WP-1) in a radioimmunoassay (RIA). Reverse-phase HPLC allows the separation of sympathetic ganglion (SG) IR-LRF from LRF decapeptide. In contrast, frog brain contains IR-LRF which is identical to LRF decapeptide on the basis of its immunological characteristics and co-chromatography with LRF decapeptide using reverse-phase HPLC. The IR-LRF of frog SG may be structurally related to LRF decapeptide." @default.
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- W2011644566 date "1980-07-01" @default.
- W2011644566 modified "2023-09-26" @default.
- W2011644566 title "Characterization of LRF-like immunoreactivity in the frog sympathetic ganglia: Non-identity with LRF decapeptide" @default.
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- W2011644566 doi "https://doi.org/10.1016/0143-4179(80)90006-2" @default.
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