FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011719452> ?p ?o ?g. }

• W2011719452 endingPage "251" @default.
• W2011719452 startingPage "247" @default.
• W2011719452 abstract "Cellular membrane receptors sense environmental changes and relay the reshaped signal through spatially and temporally organized protein-protein interactions (PPI). Many of such PPI are transient and occur in a certain cell-dependent context. Molecular switches such as kinases and GTPases are engaged in versatile PPI. Recently, we have identified dynamic interaction and reciprocal regulation of cAMP-dependent protein kinase A (PKA) and Rho-GTPase Rac signaling. We demonstrated that GTP-activated Rac acts as a dual kinase-tuning scaffold for p21-activated kinase (PAK) and PKA activities. We showed that receptor-triggered PKA trans-phosphorylation of GTP-Rac-organized PAK contributes to elevations of nuclear Erk1/2 signaling and proliferation. We discuss these recent observations and we provide additional insights how the cAMP-PKA axis might also participate in the regulation of Rac localization." @default.
• W2011719452 created "2016-06-24" @default.
• W2011719452 creator A5024427677 @default.
• W2011719452 creator A5037393542 @default.
• W2011719452 creator A5077230365 @default.
• W2011719452 date "2013-10-01" @default.
• W2011719452 modified "2023-09-28" @default.
• W2011719452 title "Interplay of PKA and Rac" @default.
• W2011719452 cites W1963705823 @default.
• W2011719452 cites W1969814333 @default.
• W2011719452 cites W1984387240 @default.
• W2011719452 cites W1984720025 @default.
• W2011719452 cites W1984826557 @default.
• W2011719452 cites W1985309852 @default.
• W2011719452 cites W1985978199 @default.
• W2011719452 cites W1987888650 @default.
• W2011719452 cites W1999575709 @default.
• W2011719452 cites W2000253969 @default.
• W2011719452 cites W2011780255 @default.
• W2011719452 cites W2019731805 @default.
• W2011719452 cites W2024377156 @default.
• W2011719452 cites W2028242823 @default.
• W2011719452 cites W2036164824 @default.
• W2011719452 cites W2042264070 @default.
• W2011719452 cites W2054259191 @default.
• W2011719452 cites W2055953592 @default.
• W2011719452 cites W2060073899 @default.
• W2011719452 cites W2060630299 @default.
• W2011719452 cites W2061684132 @default.
• W2011719452 cites W2066228546 @default.
• W2011719452 cites W2066812847 @default.
• W2011719452 cites W2067305633 @default.
• W2011719452 cites W2067677546 @default.
• W2011719452 cites W2080062782 @default.
• W2011719452 cites W2080145523 @default.
• W2011719452 cites W2080778311 @default.
• W2011719452 cites W2088359631 @default.
• W2011719452 cites W2093486460 @default.
• W2011719452 cites W2100356751 @default.
• W2011719452 cites W2102312968 @default.
• W2011719452 cites W2102424174 @default.
• W2011719452 cites W2126920991 @default.
• W2011719452 cites W2148315081 @default.
• W2011719452 cites W2154295458 @default.
• W2011719452 cites W2159876689 @default.
• W2011719452 doi "https://doi.org/10.4161/sgtp.27281" @default.
• W2011719452 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4011821" @default.
• W2011719452 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24322054" @default.
• W2011719452 hasPublicationYear "2013" @default.
• W2011719452 type Work @default.
• W2011719452 sameAs 2011719452 @default.
• W2011719452 citedByCount "10" @default.
• W2011719452 countsByYear W20117194522015 @default.
• W2011719452 countsByYear W20117194522016 @default.
• W2011719452 countsByYear W20117194522018 @default.
• W2011719452 countsByYear W20117194522019 @default.
• W2011719452 countsByYear W20117194522020 @default.
• W2011719452 countsByYear W20117194522022 @default.
• W2011719452 crossrefType "journal-article" @default.
• W2011719452 hasAuthorship W2011719452A5024427677 @default.
• W2011719452 hasAuthorship W2011719452A5037393542 @default.
• W2011719452 hasAuthorship W2011719452A5077230365 @default.
• W2011719452 hasBestOaLocation W20117194521 @default.
• W2011719452 hasConcept C118716 @default.
• W2011719452 hasConcept C11960822 @default.
• W2011719452 hasConcept C135285700 @default.
• W2011719452 hasConcept C151730666 @default.
• W2011719452 hasConcept C181199279 @default.
• W2011719452 hasConcept C184235292 @default.
• W2011719452 hasConcept C207332259 @default.
• W2011719452 hasConcept C2779343474 @default.
• W2011719452 hasConcept C53645450 @default.
• W2011719452 hasConcept C55493867 @default.
• W2011719452 hasConcept C62478195 @default.
• W2011719452 hasConcept C80631254 @default.
• W2011719452 hasConcept C86803240 @default.
• W2011719452 hasConcept C95444343 @default.
• W2011719452 hasConcept C97029542 @default.
• W2011719452 hasConceptScore W2011719452C118716 @default.
• W2011719452 hasConceptScore W2011719452C11960822 @default.
• W2011719452 hasConceptScore W2011719452C135285700 @default.
• W2011719452 hasConceptScore W2011719452C151730666 @default.
• W2011719452 hasConceptScore W2011719452C181199279 @default.
• W2011719452 hasConceptScore W2011719452C184235292 @default.
• W2011719452 hasConceptScore W2011719452C207332259 @default.
• W2011719452 hasConceptScore W2011719452C2779343474 @default.
• W2011719452 hasConceptScore W2011719452C53645450 @default.
• W2011719452 hasConceptScore W2011719452C55493867 @default.
• W2011719452 hasConceptScore W2011719452C62478195 @default.
• W2011719452 hasConceptScore W2011719452C80631254 @default.
• W2011719452 hasConceptScore W2011719452C86803240 @default.
• W2011719452 hasConceptScore W2011719452C95444343 @default.
• W2011719452 hasConceptScore W2011719452C97029542 @default.
• W2011719452 hasIssue "4" @default.
• W2011719452 hasLocation W20117194521 @default.
• W2011719452 hasLocation W20117194522 @default.
• W2011719452 hasLocation W20117194523 @default.
• W2011719452 hasLocation W20117194524 @default.

• next