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- W2011738672 abstract "The basis for recommending prenatal diagnosis for women 35 or older has been that they have most of the infants with Down's syndrome. The cost of testing these mothers has been considered less than the institutional care of many of their infants. We found this is no longer true. Infants with Down's syndrome are more likely to be born to mothers less than 35. This trend is also true of patients with Down's syndrome at institutions. Among 18,155 infants bom from 1972 to 1975 at the Boston Hospital for Women, there were 20 with Dram's syndrome. All had trisomy 21. 65% were born to women less than 35. Only 35% were born to women 35 or older. 7% of all mothers were 35 or older. In reviewing the ages of the parents of 187 persons with Down's syndrome living in an institution for the retarded, we found a steady decline in the parental ages between the 1920's and the 1960's. If most infants with Down's syndrome are to be identified by prenatal diagnosis, current recojimendations for the ages at which routine prenatal testing is reconmended must be changed." @default.
- W2011738672 created "2016-06-24" @default.
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- W2011738672 date "1977-04-01" @default.
- W2011738672 modified "2023-10-17" @default.
- W2011738672 title "DOWN'S SYNDROME: SHIFTING PATTERNS IN MATERNAL AGE" @default.
- W2011738672 doi "https://doi.org/10.1203/00006450-197704000-00400" @default.
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