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• W2011739108 abstract "The effects of heatstroke on the structure and function of the liver have been studied in thirty-nine Bantu gold miners. Hepatocellular damage was found to be invariable. In a minority of patients (about 10 per cent) the liver damage was severe and may have contributed to a fatal outcome. In the remainder it was mild or moderate and could be detected only on biochemical testing or liver biopsy. The pathologic changes consisted of centrolobular degeneration or necrosis of hepatocytes and congestion; cholestasis and portal venular dilatation were prominent in the fatal cases. In the patients who survived, the histologic and biochemical abnormalities were completely reversible. It is suggested that the hepatic changes are the result of a combination of hypoxia and direct thermal injury. The effects of heatstroke on the structure and function of the liver have been studied in thirty-nine Bantu gold miners. Hepatocellular damage was found to be invariable. In a minority of patients (about 10 per cent) the liver damage was severe and may have contributed to a fatal outcome. In the remainder it was mild or moderate and could be detected only on biochemical testing or liver biopsy. The pathologic changes consisted of centrolobular degeneration or necrosis of hepatocytes and congestion; cholestasis and portal venular dilatation were prominent in the fatal cases. In the patients who survived, the histologic and biochemical abnormalities were completely reversible. It is suggested that the hepatic changes are the result of a combination of hypoxia and direct thermal injury." @default.
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• W2011739108 date "1970-08-01" @default.
• W2011739108 modified "2023-10-18" @default.
• W2011739108 title "Liver damage in heatstroke" @default.
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• W2011739108 doi "https://doi.org/10.1016/s0002-9343(70)80075-4" @default.
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