Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011749979> ?p ?o ?g. }
- W2011749979 endingPage "347" @default.
- W2011749979 startingPage "334" @default.
- W2011749979 abstract "Annals of the New York Academy of SciencesVolume 825, Issue 1 p. 334-347 Astrocyte Metallothioneins (MTs) and Their Neuroprotective Rolea MICHAEL ASCHNER, Corresponding Author MICHAEL ASCHNER Department of Physiology and Pharmacology Bowman Gray School of Medicine of Wake Forest University Medical Center Boulevard Winston-Salem, North Carolina 27157-1083 Tel: (910) 716-8530; fax: (910) 716 8501; e-mail: [email protected]Search for more papers by this author MICHAEL ASCHNER, Corresponding Author MICHAEL ASCHNER Department of Physiology and Pharmacology Bowman Gray School of Medicine of Wake Forest University Medical Center Boulevard Winston-Salem, North Carolina 27157-1083 Tel: (910) 716-8530; fax: (910) 716 8501; e-mail: [email protected]Search for more papers by this author First published: 17 December 2006 https://doi.org/10.1111/j.1749-6632.1997.tb48445.xCitations: 49 a This review was partially supported by grants from the National Institute of Environmental Health Services ES 07331 and the Environmental Protection Agency R-819210. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL REFERENCES 1 Kimelberg, H. K. & M. D. Norenberg. 1989. Astrocytes. Sci. Am. 260: 66– 76. 2 Kimelberg, H. K. & M. Aschner. 1994. Astrocytes and their functions, past and present. In National Institute on Alcohol Abuse and Alcoholism Research Monograph, Alcohol and Glial Cells. NIH Publication No. 94-3742. Monograph 27, 1– 40. National Institutes of Health. Bethesda , MD . 3 Lopachin, R. & M. Aschner. 1993. Glial-neuronal interactions: the relevance to neurotoxic mechanisms. Toxicol. Appl. Pharmacol. 118: 141– 158. 4 N. J. Abbot, Ed. 1991. In Glial-Neuronal Interactions. Ann. N. Y. Acad. Sci., Vol. 633. New York , NY . 5 S. Murphy, Ed. 1993. Astrocytes: Pharmacology and Function. Academic Press. New York . 6 H. Kettenman & B. Ransom, Eds. 1996, Neuroglia. Oxford University Press. New York . 7 M. Aschner & H. K. Kimelberg, Eds. 1996. The Role of Glia in Neurotoxicity. CRC Press, Boca Raton , FL . 8 Takeuchi, T. 1972. Biological reactions and pathological changes in human beings and animals caused by organic mercury contamination. In Environmental Mercury Contamination. P. Hartung & B. D. Dinman, Eds. 247– 289. Ann Arbor Science. Ann Arbor , MI . 9 Bakir, F., S. F. Damluji, L. Amin-Zaki, M. Murthada, A. Khalidi, N. Y. Al-Rawi, S. Tikriti, H. I. Dhahrir, T. W. Clarkson, J. C. Smith & R. A. Doherty. 1973. Methylmercury poisoning in Iraq. Science 181: 230– 242. 10 Brock, T. D., M. T. Madigan, J. M. Martinko & J. Parker. 1994. Biology of Microorganisms. 7th edit. 665– 666. Prentice Hall. New York . 11 Carty, A. J. & S. F. Malone. 1979. The chemistry of mercury in biological systems. In The Biogeochemistry of Mercury in the Environment. J. O. Nrigau, Ed. 433– 479. Elsevier/North Holland Biomedical Press. Amsterdam . 12 Jensen, S. & A. Jernelov. 1969. Biological methylation of mercury in aquatic organisms. Nature 223: 753– 754. 13 Wood, J. M., F. S. Kennedy & C. E. Rosen. 1968. Synthesis of methylmercury compounds by extracts of methanogenic bacterium. Nature 220: 173– 174. 14 Veiga, M. M., J. A. Meech & N. Onate. 1994. Mercury pollution from deforestation. Nature 368: 816– 817. 15 Stokes, P. M. & C. D. Wren. 1987. Bioaccumulation of mercury by aquatic biota in hydroelectric reservoirs: a review and consideration of mechanisms. In Lead, Mercury. and Arsenic in the Environment. T. C. Hutchinson & K. M. Meema, Eds. 255– 278. John Wiley and Sons. New York . 16 Pfeiffer, W. C., L. D. Lacerda, W. Salomons & O. Malm. 1993. Environmental fate of mercury from gold mining in the Brazilian Amazon. Environ. Sci. Technol. 9: 41– 46. 17 Oyake, Y., M. Tanaka, H. Kubo & H. Cichibu. 1966. Neuropathological studies on organic mercury poisoning with special reference to the staining and distribution of mercury granules. Adv. Neurol. Sci. 10: 744– 750. 18 Garman, R. H., B. Weiss & K. L. Evans. 1975. Alkylmercurial encephalopathy in the monkey; a histopathologic and autoradiographic study. Acta Neuropathol. (Berlin) 32: 61– 74. 19 Charleston, J. S., R. P. Bolender, N. K. Mottet, R. L. Body, M. E. Vahter & T. M. Burbacher. 1994. Increases in the number of reactive glia in the visual cortex of Macaca fascicularis following subclinical long-term methyl mercury exposure. Toxicol Appl. Pharmacol. 129: 196– 206. 20 Brookes, N. & D. A. Kristt. 1989. Inhibition of amino acid transport and protein synthesis by HgCl2 and methylmercury in astrocytes: selectivity and reversibility. J. Neurochem. 53: 1228– 1237. 21 Dave, V., K. J. Mullaney, S. Goderie, H. K. Kimelberg & M. Aschner. 1994. Astrocytes as mediators of methylmercury (MeHg) neurotoxicity: effects on D-aspartate and serotonin uptake. Dev. Neurosci. 16: 222– 231. 22 Brookes, N. 1992. In vitro evidence for the role of glutamate in the CNS toxicity of mercury. Toxicol. 76: 245– 256. 23 Aschner, M., Y.-L. Du, M. Gannon & H. K. Kimelberg. 1993. Methylmercury-induced alterations in excitatory amino acid efflux from rat primary astrocyte cultures. Brain Res. 602: 181– 186. 24 Vahter, N., N. K. Mottet, L. T. Friberg, B. Lind, D. D. Shen & T. M. Burbacher, 1994. Speciation of mercury in primate blood and brain following long-term exposure to methyl mercury. Toxicol. Appl. Pharmacol. 124: 221– 229. 25 Choi, D. W. 1988. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1: 623– 634. 26 Klatzo, I. 1967. Presidential address: neuropathological aspects of brain edema. J. Neuropathol. Exp. Neurol. 26: 1– 13. 27 Aschner, M., N. Eberle, K. Miller & H. K. Kimelberg. 1990. Interaction of methyl-mercury with rat primary astrocyte cultures: effects on rubidium uptake and efflux and induction of swelling. Brain Res. 530: 245– 250. 28 Coyle, J. T. & P. Puttfarcken. 1993. Oxidative stress, glutamate, and neurodegenerative disorders. Science 262: 689– 695. 29 Hertz, L. 1979. Functional interactions between neurons and astrocytes. I. Turnover and metabolism of putative amino acid transmitters. Prog. Neurobiol. 13: 277– 323. 30 Martinez-Hernandez, A., K. P. Bell & M. D. Norenberg. 1977. Glutamine synthetase: glial localization in brain. Science 195: 1356– 1358. 31 Norenberg, M. D. 1977. The distribution of glutamine synthetase in the central nervous system. J. Histochem. Cytochem. 27: 469– 475. 32 Norenberg, M. D. & A. Martinez-Hernandez. 1979. Fine structural localization of glutamine synthetase in astrocytes of rat brain. Brain Res. 161: 303– 310. 33 Schousboe, A. & I. Divac. 1979. Differences in glutamate uptake in astrocytes cultured from different brain regions. Brain Res. 177: 407– 409. 34 Jenkins, L. W., J. T. Povlishock, D. P. Becker, J. D. Miller & H. G. Sullivan. 1979. Complete cerebral ischemia: an ultrastructural study. Acta Neuropathol. (Berlin) 48: 113– 125. 35 Garcia, J. H. 1984. Experimental ischemic stroke: a review. Stroke 15: 5– 14. 36 Kimelberg, H. K., S. M. Biddlecome & R. S. Bourke. 1979. SITS-inhibitable Cl− transport and Na+-dependent H+ production in primary astroglial cultures. Brain Res. 173: 111– 124. 37 Kempski, O., F. Staub, F. V. Rosen, M. Zimmer, A. Neu & A. Baethmann. 1988. Molecular mechanisms of glial swelling in vitro. Neurochem. Pathol. 9: 109– 125. 38 Bourke, R. S., H. K. Kimelberg, M. Daze & G. Church. 1983. Swelling and ion uptake in cat cerebrocortical slices: control by neurotransmitters and ion transport mechanisms. Neurochem. Res. 8: 5– 24. 39 Van Harreveld, A. & E. Fifkova. 1971. Light and electron-microscopic changes in central nervous tissue after electrophoretic injection of glutamate. Exp. Mol. Pathol. 15: 61– 81. 40 Szatkowski, M., B. Barbour & D. Attwell. 1991. Potassium-dependence of excitatory amino acid transport: resolution of a paradox. Brain Res. 555: 343– 345. 41 Walz, W. 1992. Mechanism of rapid K+-induced swelling of mouse astrocytes. Neurosci. Lett. 135: 243– 246. 42 Barres, B. A., L. L. Y. Chun & D. P. Corey. 1990. Ion channels in vertebrate glia. Annu. Rev. Neurosci. 13: 441– 474. 43 Jalonen, T. 1993. Single-channel characteristics of the large-conductance anion channel in rat cortical astrocytes in primary culture. Glia 9: 227– 237. 44 Oliver, C. N., P. E. Stake-Reed, E. R. Stadtman, G. L. Liu, J. M. Carney & R. A. Floyd. 1990. Oxidative damage to brain proteins, loss of glutamine synthetase activity and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain. Proc. Natl. Acad. Sci. USA 87: 5144– 5147. 45 Hall, E. D., P. K. Andrus & P. A. Yonkers. 1993. Brain hydroxyl radical generation in acute experimental head injury. J. Neurochem. 60: 588– 594. 46 Hall, E. D., J. M. Braughler & J. M. Mccall. 1992. Antioxidant effects in brain and spinal cord injury. J. Neurotrauma 9: S165– S172. 47 Hager, L. G. & R. D. Palmiter. 1981. Transcriptional regulation of mouse liver metallothionein-I gene by glucocorticoids. Nature 291: 340– 342. 48 Durnam, D. M. & R. D. Palmiter. 1984. Induction of metallothionein-I mRNA in cultured cells by heavy metals and iodoacetate: evidence for gratuitous inducers. Mol. Cell. Biol. 4: 484– 491. 49 Hamer, D. H. 1986. Metallothionein. Annu. Rev. Biochem. 55: 913– 951. 50 Bremner, I. 1987. Interactions between metallothionein and trace elements. Prog. Food Nutr. Sci. 11: 1– 37. 51 Dunn, M. A., T. L. Blalock & R. J. Cousins. 1987. Metallothionein. Proc. Soc. Exp. Biol. Med. 185: 107– 119. 52 Kägi, J. H. R. & Y. Kojima. 1987. Chemistry and biochemistry of metallothionein. Experientia 52: S25– S61. 53 Kägi, J. H. R., & A. Schaffer. 1988. Biochemistry of metallothionein. Biochem. 27: 8509– 8515. 54 Kägi, J. H. R. 1991. Overview of metallothionein. In Methods in Enzymology. Vol. 205. Metallobiochemistry, Part B, Metallothionein and Related Molecules. J. F. Riordan & B. L. Vallee, Eds. 613– 626. Academic Press. New York . 55 Vallee, B. L. & V. Maret. 1993. The functional and potential functions of metallothioneins: a personal perspective. In Metallothionein III: Biological Roles and Medical Implications. K. T. Suzuki, N. Imura & M. Kimura, Eds. 1– 27. Birkhäuser Verlag. Berlin . 56 Aschner, M., M. G. Cherian, C. D. Klasssen, R. D. Palmiter, J. C. Erickson & A. I. Bush. 1996. Metallothioneins in brain—the role in physiology and pathology. Toxicol. Appl. Pharmacol. In press. 57 Aschner, M. 1996. The functional significance of brain metallothioneins. FASEB J In press. 58 Dalton, T., R. D. Palmiter & G. K. Andrews. 1994. Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant-response element and metal response promoter elements. Nucleic Acids Res. 22: 5016– 5023. 59 Searle, P. F., G. W. Stuart & R. D. Palmiter. 1987. Metal regulatory elements of the mouse metallothionein-I gene. Experientia 52: S407– S414. 60 Andrews, G. K. 1990. Regulation of metallothionein gene expression. Prog. Food Nutr. Sci. 14: 193– 258. 61 Searle, P. F., B. L. Davison, G. W. Stuart, T. M. Wilkie, G. Norstedt & R. D. Palmiter. 1984. Regulation, linkage, and sequence of mouse metallothionein I and II genes. Mol. Cell. Biol. 4: 1221– 1230. 62 Radtke, F., R. Heuchel, O. Georgiev, M. Hergersberg, M. Gariglio, Z. Dembic & W. Schaffner. 1993. Cloned transcription factor MTF-I activates the mouse metallothionein promoter. EMBO J. 12: 1355– 1362. 63 Heuchel, R., F. Radtke, O. Georgiev, G. Stark, M. Aguet & W. Schaffner. 1994. The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression. EMBO J. 13: 2870– 2875. 64 Palmiter, R. D. 1994. Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1. Proc. Natl. Acad. Sci. USA 91: 1219– 1223. 65 Uchida, Y., K. Takio, K. Titani, Y. Ihara & M. Tomonaga. 1991. The growth inhibitory factor that is deficient in Alzheimer's disease is a 68 amino acid metallothionein-like protein. Neuron 7: 337– 347. 66 Palmiter, R. D., S. D. Findley, T. E. Whitmore & D. M. Durnam. 1992. MT-III, a brain-specific member of the metallothionein family. Proc. Natl. Acad. Sci. USA 89: 6333– 6337. 67 Quaife, C. J., S. D. Findley, J. C. Erickson, G. J. Froelick, E. J. Kelly. B. P. Zambrowicz & R. D. Palmiter. 1994. Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia. Biochemistry 33: 7250– 7259. 68 Choudhuri, S., K. K. Kramer, N. E. Herman, T. P. Dalton, G. K. Andrews & C. D. Klaassen. 1995. Constitutive expression of metallothionein genes in mouse brains. Toxicol. Appl. Pharmacol. 131: 144– 154. 69 Yagle, M. K. & R. D. Palmiter. 1985. Coordinate regulation of mouse metallothionein I and II genes by heavy metals and glucocorticoids. Mol. Cell. Biol. 5: 291– 294. 70 Masters, B. A., C. J. Quaife, J. C. Erickson, E. J. Kelly, G. J. Froelick, B. P. Zambrowicz, R. L. Brinster & R. D. Palmiter. 1994. Metallothionein III is expressed in neurons that sequester zinc in synaptic vesicles. J. Neurosci. 14: 5844– 5857. 71 Nishimura, N., H. Nishimura, A. Ghaffar & C. Tohyama. 1992. Localization of metallothionein in the brain of rat and mouse. J. Histochem. Cytochem. 40: 309– 315. 72 Suzuki, K., K. Nakajima, U. Kawaharada, U. Uehara, F. Hara, N. Otaki, M. Kimura & Y. Tamura. 1992. Metallothionein in the human brain. Acta Histochem. Cytochem. 25: 617– 622. 73 Young, J. K., J. S. Garvey & P. C. Huang. 1991. Glial immunoreactivity for metallothionein in the rat brain. Glia 4: 602– 610. 74 Blaauwgeers, H. G., P. A. Sillevis-Smitt, J. A. De-Jong & D. Troost, 1993. Distribution of metallothionein in the human central nervous system. Glia 8: 62– 70. 75 Hidalgo, J., A. Garcia, A. M. Oliva, M. Giralt, T. Gasull, B. Gonzales, H. Milnerowicz, A. Wood & I. Bremner. 1994. Effect of zinc, copper and glucocorticoids on metallothionein levels of cultured neurons and astrocytes from rat brain. Chem. Biol. Interact. 93: 197– 219. 76 Young, J. K. 1994. Glial metallothionein. Biol. Signals 3: 169– 175. 77 Lazo, J. S., Y. Kondo, D. Dellapiazza, A. E. Michalska, K. H. A. Choo & B. R. Pitt. 1995. Enhanced sensitivity to oxidative stress in cultured embryonic cells from transgenic mice deficient in metallothionein I and II genes. J. Biol. Chem. 270: 5506– 5510. 78 Coogan, T. P., R. M. Bare, E. J. Bjornson & M. P. Waalkes. 1994. Enhanced metallothionein gene expression is associated with protection from cadmium-induced genotoxicity in cultured rat liver cells. J. Toxicol. Environ. Health 41: 233– 245. 79 Rhee, E. S.-J. & P. C. Huang. 1989. Metallothionein accumulation in CHO Cdr cells in response to lead treatment. Chem. Biol. Interact. 72: 347– 361. 80 Rising, L., D. Vitarella, H. K. Kimelberg & M. Aschner. 1995. Metallothionein induction in neonatal rat primary astrocyte cultures protects against methylmercury cytotoxicity. J. Neurochem. 65: 1562– 1568. 81 Vitarella, D., D. R. Conklin, H. K. Kimelberg & M. Aschner. 1996. Metallothionein (MT) induction protects swollen rat primary astrocyte cultures from methylmercury-induced inhibition of regulatory volume decrease. Brain Res. In press. 82 Hughes, W. H. 1957. A physiochemical rationale for the biological activity of mercury and its compounds. Ann. N. Y. Acad. Sci. 65: 454– 460. 83 Chen, R. W., H. E. Ganther & W. G. Hoekstra. 1973. Studies on the binding of methylmercury by thionein. Biochem. Biophys. Res. Commun. 51: 383– 390. 84 Chmielnicka, J. & E. A. Brzeznicka. 1978. The influence of selenium on the level of mercury and metallothionein in rat kidneys in prolonged exposure to different mercury compounds. Bull. Environ. Contamin. Toxicol. 19: 183– 190. 85 Leyshon-Sørland, K., B. Jasani & A. J. Morgan. 1994. The localization of mercury and metallothionein in the cerebellum of rats experimentally exposed to methylmercury. Histochem. J. 26: 161– 169. 86 Sato, M. & I. Bremner. 1993. Oxygen free radicals and metallothionein. Free Radical Biol. Med. 14: 325– 337. 87 Yee, S. & B. H. Choi. 1994. Methylmercury poisoning induces oxidative stress in the mouse brain. Exp. Mol. Pathol. 60: 188– 196. 88 Charleston, J. S., R. L. Body, N. K. Mottet, M. E. Vahter & T. M. Burbacher. 1995. Autometallographic determination of inorganic mercury distribution in the cortex of the calcarine sulcus of the monkey Macaca fascicularis following long-term subclinical exposure to methylmercury and mercuric chloride. Toxicol. Appl. Pharmacol 132: 325– 333. 89 Vahter, M. E., N. K. Mottet, L. T. Friberg, S. B. Lind, J. S. Charleston & T. M. Burbacher. 1995. Demethylation of methyl mercury in different brain sites of Macaca fascicularis monkeys during long-term subclinical methylmercury exposure. Toxicol. Appl. Pharmacol. 134: 273– 284. 90 Palmiter, R. D. 1995. Submitted. Citing Literature Volume825, Issue1Neuroprotective Agents: Third International ConferenceOctober 1997Pages 334-347 ReferencesRelatedInformation" @default.
- W2011749979 created "2016-06-24" @default.
- W2011749979 creator A5035503566 @default.
- W2011749979 date "1997-10-01" @default.
- W2011749979 modified "2023-10-17" @default.
- W2011749979 title "Astrocyte Metallothioneins (MTs) and Their Neuroprotective Role<sup>a</sup>" @default.
- W2011749979 cites W1670939209 @default.
- W2011749979 cites W1955702721 @default.
- W2011749979 cites W196233321 @default.
- W2011749979 cites W1966153026 @default.
- W2011749979 cites W1975512627 @default.
- W2011749979 cites W1984089779 @default.
- W2011749979 cites W1987080089 @default.
- W2011749979 cites W1988432717 @default.
- W2011749979 cites W1989810120 @default.
- W2011749979 cites W1991000845 @default.
- W2011749979 cites W1993724975 @default.
- W2011749979 cites W1994137439 @default.
- W2011749979 cites W1998723021 @default.
- W2011749979 cites W2002632630 @default.
- W2011749979 cites W2009016920 @default.
- W2011749979 cites W2009639605 @default.
- W2011749979 cites W2009788226 @default.
- W2011749979 cites W2012934845 @default.
- W2011749979 cites W2016293448 @default.
- W2011749979 cites W2016575029 @default.
- W2011749979 cites W2020891290 @default.
- W2011749979 cites W2021061739 @default.
- W2011749979 cites W2023468397 @default.
- W2011749979 cites W2024547006 @default.
- W2011749979 cites W2026155540 @default.
- W2011749979 cites W2027217372 @default.
- W2011749979 cites W2027452172 @default.
- W2011749979 cites W2031298547 @default.
- W2011749979 cites W2032458072 @default.
- W2011749979 cites W2036394095 @default.
- W2011749979 cites W2038962521 @default.
- W2011749979 cites W2041641901 @default.
- W2011749979 cites W2042894136 @default.
- W2011749979 cites W2043985651 @default.
- W2011749979 cites W2048135120 @default.
- W2011749979 cites W2048766756 @default.
- W2011749979 cites W2055780194 @default.
- W2011749979 cites W2058525427 @default.
- W2011749979 cites W2058796783 @default.
- W2011749979 cites W2058897268 @default.
- W2011749979 cites W2059075664 @default.
- W2011749979 cites W2064378885 @default.
- W2011749979 cites W2064857569 @default.
- W2011749979 cites W2065264404 @default.
- W2011749979 cites W2065939959 @default.
- W2011749979 cites W2085465359 @default.
- W2011749979 cites W2088125189 @default.
- W2011749979 cites W2089526912 @default.
- W2011749979 cites W2094705784 @default.
- W2011749979 cites W2099018685 @default.
- W2011749979 cites W2108373851 @default.
- W2011749979 cites W2109103599 @default.
- W2011749979 cites W2118296350 @default.
- W2011749979 cites W2143546229 @default.
- W2011749979 cites W2143609309 @default.
- W2011749979 cites W2153685597 @default.
- W2011749979 cites W2155142285 @default.
- W2011749979 cites W2166439728 @default.
- W2011749979 cites W2169859443 @default.
- W2011749979 cites W2885026210 @default.
- W2011749979 cites W2887646526 @default.
- W2011749979 cites W310193716 @default.
- W2011749979 cites W4238401914 @default.
- W2011749979 cites W4243065863 @default.
- W2011749979 cites W4245465591 @default.
- W2011749979 cites W4250221563 @default.
- W2011749979 cites W4254543881 @default.
- W2011749979 doi "https://doi.org/10.1111/j.1749-6632.1997.tb48445.x" @default.
- W2011749979 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9369999" @default.
- W2011749979 hasPublicationYear "1997" @default.
- W2011749979 type Work @default.
- W2011749979 sameAs 2011749979 @default.
- W2011749979 citedByCount "68" @default.
- W2011749979 countsByYear W20117499792012 @default.
- W2011749979 countsByYear W20117499792013 @default.
- W2011749979 countsByYear W20117499792014 @default.
- W2011749979 countsByYear W20117499792015 @default.
- W2011749979 countsByYear W20117499792016 @default.
- W2011749979 countsByYear W20117499792017 @default.
- W2011749979 countsByYear W20117499792018 @default.
- W2011749979 countsByYear W20117499792019 @default.
- W2011749979 countsByYear W20117499792020 @default.
- W2011749979 countsByYear W20117499792021 @default.
- W2011749979 countsByYear W20117499792022 @default.
- W2011749979 countsByYear W20117499792023 @default.
- W2011749979 crossrefType "journal-article" @default.
- W2011749979 hasAuthorship W2011749979A5035503566 @default.
- W2011749979 hasConcept C169760540 @default.
- W2011749979 hasConcept C185592680 @default.
- W2011749979 hasConcept C25498285 @default.
- W2011749979 hasConcept C2777542381 @default.
- W2011749979 hasConcept C529278444 @default.