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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011775503> ?p ?o ?g. }

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• W2011775503 abstract "The present study provides the first evidence that fibroblasts obtained from patients affected by Crouzon syndrome, a rare craniosynostosis, despite mutations in the high-affinity bFGF receptor retain their capacity to respond to bFGF. The growth factor reduces IL-1 secretion, downregulates biglycan and procollagen alpha(1)(I), and increases betaglycan expression. Since betaglycan is a co-receptor for bFGF signalling, an alternative signal transduction pathway is suggested in Crouzon fibroblasts, to explain the documented changes in ECM macromolecule production." @default.
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• W2011775503 date "2000-08-01" @default.
• W2011775503 modified "2023-09-27" @default.
• W2011775503 title "INTERLEUKIN SECRETION, PROTEOGLYCAN AND PROCOLLAGEN α1(I) GENE EXPRESSION IN CROUZON FIBROBLASTS TREATED WITH BASIC FIBROBLAST GROWTH FACTOR" @default.
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• W2011775503 doi "https://doi.org/10.1006/cyto.1999.0730" @default.
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