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• W2011776534 abstract "Cultured striatal neurons containing either NADPH-diaphorase or acetylcholinesterase were more resistant to injury by N- methyl- d -aspartate (NMDA) or quinolinate, than the general striatal neuronal population, although this resistance was not absolute and could be overcome by intense toxic exposure. Neurons containing NADPH-diaphorase, but not neurons containing acetylcholinesterase, also exhibited heightened vulnerability to injury by kainate. Given recent evidence that diaphorase- and cholinesterase-containing striatal neurons are selectively spared in Huntington's disease, our results strengthen the possibility that NMDA receptor-mediated neurotoxicity may participate in the pathogenesis of that disease." @default.
• W2011776534 created "2016-06-24" @default.
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• W2011776534 date "1988-04-01" @default.
• W2011776534 modified "2023-09-23" @default.
• W2011776534 title "Cultured striatal neurons containing NADPH-diaphorase or acetylcholinesterase are selectively resistant to injury by NMDA receptor agonists" @default.
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• W2011776534 doi "https://doi.org/10.1016/0006-8993(88)90897-9" @default.
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