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• W2011777307 abstract "Blood cell sorting is critical to sample preparation for both clinical diagnosis and therapeutic research. The spiral inertial microfluidic devices can achieve label-free, continuous separation of cell mixtures with high throughput and efficiency. The devices utilize hydrodynamic forces acting on cells within laminar flow, coupled with rotational Dean drag due to curvilinear microchannel geometry. Here, we report on optimized Archimedean spiral devices to achieve cell separation in less than 8 cm of downstream focusing length. These improved devices are small in size (<1 in.(2)), exhibit high separation efficiency (∼95%), and high throughput with rates up to 1 × 10(6) cells per minute. These device concepts offer a path towards possible development of a lab-on-chip for point-of-care blood analysis with high efficiency, low cost, and reduced analysis time." @default.
• W2011777307 created "2016-06-24" @default.
• W2011777307 creator A5030378040 @default.
• W2011777307 creator A5051277777 @default.
• W2011777307 date "2013-09-01" @default.
• W2011777307 modified "2023-10-14" @default.
• W2011777307 title "Continuous separation of blood cells in spiral microfluidic devices" @default.
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• W2011777307 doi "https://doi.org/10.1063/1.4819275" @default.
• W2011777307 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3779264" @default.
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• W2011777307 hasPublicationYear "2013" @default.
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