Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011777524> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2011777524 endingPage "140" @default.
- W2011777524 startingPage "135" @default.
- W2011777524 abstract "The ability of reduced polycyclic aromatic hydrocarbons to be converted to their fully aromatic forms by the microsomal cytochrome P-450 mixed-function oxidases may assist in the explanation of the mutagenic and tumorigenic activities of these agents. The metabolic conversion of 9,10-dihydrobenzo[a]pyrene (9,10-DHB[a]P) to benzo[a]pyrene (B[a]P) and 9- and/or 10-hydroxy-9,10-DHB[a]P (OH-9,10-DHB[a]P) was quantitatively measured. In β-naphthoflavone-induced rat liver microsomes, 9,10-DHB[a]P was metabolized to B[a]P with a specific activity of 1.51 nmol B[a]P formed/min/mg microsomal protein. The formation of B[a]P was directly related to incubation time and microsomal protein concentration. Similarly, 9,10-DHB[a]P was converted to OH-9,10-DHB[a]P with a specific activity of 4.48 nmol OH-9,10-DHB[a]P formed/min/mg microsomal protein. Its formation was directly related to incubation time and microsomal protein concentration. The possibility of OH-9,10-DHB[a]P as a metabolic intermediate to B[a]P is discussed." @default.
- W2011777524 created "2016-06-24" @default.
- W2011777524 creator A5002116781 @default.
- W2011777524 creator A5008439192 @default.
- W2011777524 creator A5014221194 @default.
- W2011777524 creator A5017703510 @default.
- W2011777524 creator A5087549541 @default.
- W2011777524 date "1993-09-01" @default.
- W2011777524 modified "2023-09-26" @default.
- W2011777524 title "Quantitative analysis of the metabolism of 9,10-dihydrobenzo[a]pyrene by induced rat liver microsomes" @default.
- W2011777524 cites W1563004338 @default.
- W2011777524 cites W1602211564 @default.
- W2011777524 cites W1775749144 @default.
- W2011777524 cites W1966666947 @default.
- W2011777524 cites W2008362851 @default.
- W2011777524 cites W2048325954 @default.
- W2011777524 cites W2049216986 @default.
- W2011777524 cites W2078152013 @default.
- W2011777524 cites W4411360 @default.
- W2011777524 doi "https://doi.org/10.1016/0304-3835(93)90255-8" @default.
- W2011777524 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8221625" @default.
- W2011777524 hasPublicationYear "1993" @default.
- W2011777524 type Work @default.
- W2011777524 sameAs 2011777524 @default.
- W2011777524 citedByCount "2" @default.
- W2011777524 countsByYear W20117775242018 @default.
- W2011777524 crossrefType "journal-article" @default.
- W2011777524 hasAuthorship W2011777524A5002116781 @default.
- W2011777524 hasAuthorship W2011777524A5008439192 @default.
- W2011777524 hasAuthorship W2011777524A5014221194 @default.
- W2011777524 hasAuthorship W2011777524A5017703510 @default.
- W2011777524 hasAuthorship W2011777524A5087549541 @default.
- W2011777524 hasConcept C178790620 @default.
- W2011777524 hasConcept C181199279 @default.
- W2011777524 hasConcept C185592680 @default.
- W2011777524 hasConcept C25642318 @default.
- W2011777524 hasConcept C2776524530 @default.
- W2011777524 hasConcept C2777538855 @default.
- W2011777524 hasConcept C2778951431 @default.
- W2011777524 hasConcept C2780768313 @default.
- W2011777524 hasConcept C55493867 @default.
- W2011777524 hasConcept C62231903 @default.
- W2011777524 hasConcept C87644729 @default.
- W2011777524 hasConceptScore W2011777524C178790620 @default.
- W2011777524 hasConceptScore W2011777524C181199279 @default.
- W2011777524 hasConceptScore W2011777524C185592680 @default.
- W2011777524 hasConceptScore W2011777524C25642318 @default.
- W2011777524 hasConceptScore W2011777524C2776524530 @default.
- W2011777524 hasConceptScore W2011777524C2777538855 @default.
- W2011777524 hasConceptScore W2011777524C2778951431 @default.
- W2011777524 hasConceptScore W2011777524C2780768313 @default.
- W2011777524 hasConceptScore W2011777524C55493867 @default.
- W2011777524 hasConceptScore W2011777524C62231903 @default.
- W2011777524 hasConceptScore W2011777524C87644729 @default.
- W2011777524 hasIssue "2-3" @default.
- W2011777524 hasLocation W20117775241 @default.
- W2011777524 hasLocation W20117775242 @default.
- W2011777524 hasOpenAccess W2011777524 @default.
- W2011777524 hasPrimaryLocation W20117775241 @default.
- W2011777524 hasRelatedWork W1974453544 @default.
- W2011777524 hasRelatedWork W1976487819 @default.
- W2011777524 hasRelatedWork W1981839262 @default.
- W2011777524 hasRelatedWork W2026658540 @default.
- W2011777524 hasRelatedWork W2056093467 @default.
- W2011777524 hasRelatedWork W2087294636 @default.
- W2011777524 hasRelatedWork W2183361744 @default.
- W2011777524 hasRelatedWork W2413042135 @default.
- W2011777524 hasRelatedWork W2419742715 @default.
- W2011777524 hasRelatedWork W3141578006 @default.
- W2011777524 hasVolume "73" @default.
- W2011777524 isParatext "false" @default.
- W2011777524 isRetracted "false" @default.
- W2011777524 magId "2011777524" @default.
- W2011777524 workType "article" @default.