Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011789776> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2011789776 endingPage "113" @default.
- W2011789776 startingPage "109" @default.
- W2011789776 abstract "Rotigotine, an investigational dopamine agonist formulated as a patch, is being studied in Parkinson's disease. A microdialysis technique, in combination with microbore column liquid chromatography and electrochemical detection, was developed to monitor rotigotine levels in the brain. Microdialysis probes were inserted into the striata of anesthetized rats, and samples were collected during perfusion with Ringer's solution. Rotigotine was separated using a C18 reversed-phase column. The mobile phase consisted of 50 mM Na2HPO4·2H2O, 2.5 mM sodium octyl sulfonate, and pH 4.5; 35% volume to volume acetonitrile. The flow rate was 30 μl/min, and the potential of the glassy carbon electrode was set to +850 mV. The method allowed monitoring of the time course of brain extracellular rotigotine levels with a detection limit of 1 nM following either intravenous (0.5 mg/kg) or subcutaneous (5.0 mg/kg) rotigotine injection." @default.
- W2011789776 created "2016-06-24" @default.
- W2011789776 creator A5014005682 @default.
- W2011789776 creator A5069890227 @default.
- W2011789776 creator A5077560958 @default.
- W2011789776 creator A5086473480 @default.
- W2011789776 date "2007-01-01" @default.
- W2011789776 modified "2023-10-15" @default.
- W2011789776 title "Determination of the dopamine agonist rotigotine in microdialysates from the rat brain by microbore column liquid chromatography with electrochemical detection" @default.
- W2011789776 cites W1971918238 @default.
- W2011789776 cites W1973919021 @default.
- W2011789776 cites W2023320713 @default.
- W2011789776 cites W2031467920 @default.
- W2011789776 cites W2043556151 @default.
- W2011789776 cites W2046043223 @default.
- W2011789776 cites W2065035054 @default.
- W2011789776 cites W2077441371 @default.
- W2011789776 cites W2128065985 @default.
- W2011789776 doi "https://doi.org/10.1016/j.jchromb.2006.07.066" @default.
- W2011789776 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16979391" @default.
- W2011789776 hasPublicationYear "2007" @default.
- W2011789776 type Work @default.
- W2011789776 sameAs 2011789776 @default.
- W2011789776 citedByCount "21" @default.
- W2011789776 countsByYear W20117897762012 @default.
- W2011789776 countsByYear W20117897762013 @default.
- W2011789776 countsByYear W20117897762015 @default.
- W2011789776 countsByYear W20117897762017 @default.
- W2011789776 countsByYear W20117897762018 @default.
- W2011789776 countsByYear W20117897762019 @default.
- W2011789776 countsByYear W20117897762020 @default.
- W2011789776 countsByYear W20117897762021 @default.
- W2011789776 countsByYear W20117897762022 @default.
- W2011789776 countsByYear W20117897762023 @default.
- W2011789776 crossrefType "journal-article" @default.
- W2011789776 hasAuthorship W2011789776A5014005682 @default.
- W2011789776 hasAuthorship W2011789776A5069890227 @default.
- W2011789776 hasAuthorship W2011789776A5077560958 @default.
- W2011789776 hasAuthorship W2011789776A5086473480 @default.
- W2011789776 hasConcept C119128265 @default.
- W2011789776 hasConcept C126322002 @default.
- W2011789776 hasConcept C139369640 @default.
- W2011789776 hasConcept C147789679 @default.
- W2011789776 hasConcept C17525397 @default.
- W2011789776 hasConcept C179998833 @default.
- W2011789776 hasConcept C185592680 @default.
- W2011789776 hasConcept C2779134260 @default.
- W2011789776 hasConcept C2779424955 @default.
- W2011789776 hasConcept C2779734285 @default.
- W2011789776 hasConcept C28406088 @default.
- W2011789776 hasConcept C43617362 @default.
- W2011789776 hasConcept C50156730 @default.
- W2011789776 hasConcept C52859227 @default.
- W2011789776 hasConcept C55493867 @default.
- W2011789776 hasConcept C71924100 @default.
- W2011789776 hasConceptScore W2011789776C119128265 @default.
- W2011789776 hasConceptScore W2011789776C126322002 @default.
- W2011789776 hasConceptScore W2011789776C139369640 @default.
- W2011789776 hasConceptScore W2011789776C147789679 @default.
- W2011789776 hasConceptScore W2011789776C17525397 @default.
- W2011789776 hasConceptScore W2011789776C179998833 @default.
- W2011789776 hasConceptScore W2011789776C185592680 @default.
- W2011789776 hasConceptScore W2011789776C2779134260 @default.
- W2011789776 hasConceptScore W2011789776C2779424955 @default.
- W2011789776 hasConceptScore W2011789776C2779734285 @default.
- W2011789776 hasConceptScore W2011789776C28406088 @default.
- W2011789776 hasConceptScore W2011789776C43617362 @default.
- W2011789776 hasConceptScore W2011789776C50156730 @default.
- W2011789776 hasConceptScore W2011789776C52859227 @default.
- W2011789776 hasConceptScore W2011789776C55493867 @default.
- W2011789776 hasConceptScore W2011789776C71924100 @default.
- W2011789776 hasIssue "1" @default.
- W2011789776 hasLocation W20117897761 @default.
- W2011789776 hasLocation W20117897762 @default.
- W2011789776 hasOpenAccess W2011789776 @default.
- W2011789776 hasPrimaryLocation W20117897761 @default.
- W2011789776 hasRelatedWork W1965231618 @default.
- W2011789776 hasRelatedWork W1984744089 @default.
- W2011789776 hasRelatedWork W2006193633 @default.
- W2011789776 hasRelatedWork W2006971437 @default.
- W2011789776 hasRelatedWork W2024274674 @default.
- W2011789776 hasRelatedWork W2025501647 @default.
- W2011789776 hasRelatedWork W2056343424 @default.
- W2011789776 hasRelatedWork W2118725953 @default.
- W2011789776 hasRelatedWork W2795496663 @default.
- W2011789776 hasRelatedWork W8917621 @default.
- W2011789776 hasVolume "845" @default.
- W2011789776 isParatext "false" @default.
- W2011789776 isRetracted "false" @default.
- W2011789776 magId "2011789776" @default.
- W2011789776 workType "article" @default.