FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011802116> ?p ?o ?g. }

• W2011802116 endingPage "122" @default.
• W2011802116 startingPage "117" @default.
• W2011802116 abstract "In order to increase our knowledge of the in vivo role of acidic fibroblast growth factor (aFGF) in the central nervous system, we have examined aFGF levels during mouse brain development. Using a specific polyclonal antibody raised against aFGF, we measured levels of aFGF-immunoreactive material (IRMaFGF) in extract of total mouse brain taken at different days of development. We found that the level of measurable IRMaFGF remained low and without significant variation during fetal brain development (0.2 ng/mg of extracted proteins). During the first 11 days postnatal (P0 to P11), IRMaFGF increased from 0.5 to 1.5 ng/mg. Between P11 and P14 IRMaFGF levels went up more rapidly, reaching 5 ng/mg. From P30 to adulthood a constant value of 2.5 ng/mg was measured. aFGF content in the different brain extracts was further characterized by its affinity for heparin-Sepharose, its elution at 1 M NaCl from this column and its capacity to induce thymidine incorporation in quiescent fibroblasts. These results were confirmed at the mRNA level. Northern blot analyses of poly A+ mRNA from brains with a specific riboprobe for bovine aFGF, revealed a major 4.5-Kb transcript and a minor 2.7-Kb transcript detectable only in postnatal brains. A similar pattern to that observed for IRMaFGF was seen with these mRNA transcripts, indicating that these aFGFmRNA are translated in the mouse brain. Our results suggest that aFGF may act in the postnatal phases of brain maturation." @default.
• W2011802116 created "2016-06-24" @default.
• W2011802116 creator A5003023717 @default.
• W2011802116 creator A5006249991 @default.
• W2011802116 creator A5024734107 @default.
• W2011802116 creator A5040573508 @default.
• W2011802116 creator A5045351120 @default.
• W2011802116 creator A5066390679 @default.
• W2011802116 creator A5077551257 @default.
• W2011802116 date "1991-04-01" @default.
• W2011802116 modified "2023-10-14" @default.
• W2011802116 title "Developmental changes of acidic fibroblast growth factor (aFGF) transcription and expression in mouse brain" @default.
• W2011802116 cites W1862567903 @default.
• W2011802116 cites W1963870770 @default.
• W2011802116 cites W1969235095 @default.
• W2011802116 cites W1971671659 @default.
• W2011802116 cites W1973647216 @default.
• W2011802116 cites W1984648137 @default.
• W2011802116 cites W1994959844 @default.
• W2011802116 cites W1999675886 @default.
• W2011802116 cites W2011469489 @default.
• W2011802116 cites W2011495255 @default.
• W2011802116 cites W2015753530 @default.
• W2011802116 cites W2020380428 @default.
• W2011802116 cites W2020771907 @default.
• W2011802116 cites W2021092333 @default.
• W2011802116 cites W2028236388 @default.
• W2011802116 cites W2028411950 @default.
• W2011802116 cites W2028820273 @default.
• W2011802116 cites W2032215155 @default.
• W2011802116 cites W2034158287 @default.
• W2011802116 cites W2051485994 @default.
• W2011802116 cites W2055164554 @default.
• W2011802116 cites W2059566787 @default.
• W2011802116 cites W2060333964 @default.
• W2011802116 cites W2060415848 @default.
• W2011802116 cites W2060630768 @default.
• W2011802116 cites W2063695629 @default.
• W2011802116 cites W2070307663 @default.
• W2011802116 cites W2074527580 @default.
• W2011802116 cites W2084098131 @default.
• W2011802116 cites W2088196028 @default.
• W2011802116 cites W2099543104 @default.
• W2011802116 cites W2110496174 @default.
• W2011802116 cites W2151598389 @default.
• W2011802116 cites W2163958271 @default.
• W2011802116 cites W2396748657 @default.
• W2011802116 cites W2404947585 @default.
• W2011802116 cites W4255042798 @default.
• W2011802116 doi "https://doi.org/10.1016/0165-3806(91)90091-v" @default.
• W2011802116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1717176" @default.
• W2011802116 hasPublicationYear "1991" @default.
• W2011802116 type Work @default.
• W2011802116 sameAs 2011802116 @default.
• W2011802116 citedByCount "18" @default.
• W2011802116 crossrefType "journal-article" @default.
• W2011802116 hasAuthorship W2011802116A5003023717 @default.
• W2011802116 hasAuthorship W2011802116A5006249991 @default.
• W2011802116 hasAuthorship W2011802116A5024734107 @default.
• W2011802116 hasAuthorship W2011802116A5040573508 @default.
• W2011802116 hasAuthorship W2011802116A5045351120 @default.
• W2011802116 hasAuthorship W2011802116A5066390679 @default.
• W2011802116 hasAuthorship W2011802116A5077551257 @default.
• W2011802116 hasConcept C104317684 @default.
• W2011802116 hasConcept C105580179 @default.
• W2011802116 hasConcept C126322002 @default.
• W2011802116 hasConcept C134018914 @default.
• W2011802116 hasConcept C153911025 @default.
• W2011802116 hasConcept C159654299 @default.
• W2011802116 hasConcept C170493617 @default.
• W2011802116 hasConcept C177707886 @default.
• W2011802116 hasConcept C203014093 @default.
• W2011802116 hasConcept C207001950 @default.
• W2011802116 hasConcept C2778837531 @default.
• W2011802116 hasConcept C54355233 @default.
• W2011802116 hasConcept C55493867 @default.
• W2011802116 hasConcept C71924100 @default.
• W2011802116 hasConcept C74373430 @default.
• W2011802116 hasConcept C81439078 @default.
• W2011802116 hasConcept C86803240 @default.
• W2011802116 hasConcept C956191 @default.
• W2011802116 hasConceptScore W2011802116C104317684 @default.
• W2011802116 hasConceptScore W2011802116C105580179 @default.
• W2011802116 hasConceptScore W2011802116C126322002 @default.
• W2011802116 hasConceptScore W2011802116C134018914 @default.
• W2011802116 hasConceptScore W2011802116C153911025 @default.
• W2011802116 hasConceptScore W2011802116C159654299 @default.
• W2011802116 hasConceptScore W2011802116C170493617 @default.
• W2011802116 hasConceptScore W2011802116C177707886 @default.
• W2011802116 hasConceptScore W2011802116C203014093 @default.
• W2011802116 hasConceptScore W2011802116C207001950 @default.
• W2011802116 hasConceptScore W2011802116C2778837531 @default.
• W2011802116 hasConceptScore W2011802116C54355233 @default.
• W2011802116 hasConceptScore W2011802116C55493867 @default.
• W2011802116 hasConceptScore W2011802116C71924100 @default.
• W2011802116 hasConceptScore W2011802116C74373430 @default.
• W2011802116 hasConceptScore W2011802116C81439078 @default.
• W2011802116 hasConceptScore W2011802116C86803240 @default.

• next