Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011833035> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2011833035 endingPage "125" @default.
- W2011833035 startingPage "117" @default.
- W2011833035 abstract "Tubulin is the major constituent protein of microtubules. In mammals, there are seven beta-tubulins and six alpha-tubulins. Each beta-tubulin isotype has a unique tissue distribution. The purpose of this study was to describe the distribution of tubulin beta II in normal and neoplastic human tissues with immunohistochemical techniques. We obtained normal tissues from 33 cases (8 fetuses, 17 neonates, 3 children and 5 adults) and 121 samples of neoplastic tissue from surgical specimens or at autopsy. Immunohistochemical staining for tubulin beta II was performed using a monoclonal antibody, KNY379 developed in our laboratory. Tubulin beta II was detected in various normal tissues, particularly in fetal and neonatal tissues, such as the nervous system, pulmonary alveoli, bronchioles and bronchi, colon, pancreatic ducts and acini, renal convoluted tubuli, skin epidermis, body cavity mesothelial cells, smooth muscle and thymus. In the adult, broad expression was also observed; however, the immunoreactivity was weaker and the extent of its distribution decreased with age. In neoplastic tissues, tubulin beta II immunoreactivity was detected in various nervous system neoplasms and other neoplasms such as pancreatic solid cystic carcinoma, pleomorphic adenoma, Warthin's tumor, nephroblastoma, basal cell carcinoma and malignant mesothelioma. We conclude that our monoclonal antibody, KNY379, may be useful as a marker of nervous system neoplasm, pancreatic solid cystic carcinoma, pleomorphic adenoma, Warthin's tumor, nephroblastoma, basal cell carcinoma and malignant mesothelioma." @default.
- W2011833035 created "2016-06-24" @default.
- W2011833035 creator A5038221128 @default.
- W2011833035 creator A5055441770 @default.
- W2011833035 creator A5060379363 @default.
- W2011833035 creator A5090501626 @default.
- W2011833035 date "2005-01-01" @default.
- W2011833035 modified "2023-09-27" @default.
- W2011833035 title "Immunohistochemical Distribution of Tubulin beta II in Human Normal and Neoplastic Tissues" @default.
- W2011833035 cites W1537655275 @default.
- W2011833035 cites W1968312126 @default.
- W2011833035 cites W1969729466 @default.
- W2011833035 cites W1971910646 @default.
- W2011833035 cites W1978659501 @default.
- W2011833035 cites W1996491270 @default.
- W2011833035 cites W1997159014 @default.
- W2011833035 cites W2009914341 @default.
- W2011833035 cites W2010499872 @default.
- W2011833035 cites W2013606098 @default.
- W2011833035 cites W2040228586 @default.
- W2011833035 cites W2041753663 @default.
- W2011833035 cites W2050658031 @default.
- W2011833035 cites W2066216160 @default.
- W2011833035 cites W2072148078 @default.
- W2011833035 cites W2073705753 @default.
- W2011833035 cites W2074183288 @default.
- W2011833035 cites W2074284759 @default.
- W2011833035 cites W2076740196 @default.
- W2011833035 cites W2078342982 @default.
- W2011833035 cites W2079125505 @default.
- W2011833035 cites W2083361083 @default.
- W2011833035 cites W2090385561 @default.
- W2011833035 cites W2093042690 @default.
- W2011833035 cites W2095992748 @default.
- W2011833035 cites W2103590067 @default.
- W2011833035 cites W2116270889 @default.
- W2011833035 cites W2140804399 @default.
- W2011833035 cites W2142524812 @default.
- W2011833035 cites W2144938808 @default.
- W2011833035 cites W4247825993 @default.
- W2011833035 cites W2004605976 @default.
- W2011833035 doi "https://doi.org/10.2739/kurumemedj.52.117" @default.
- W2011833035 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16639982" @default.
- W2011833035 hasPublicationYear "2005" @default.
- W2011833035 type Work @default.
- W2011833035 sameAs 2011833035 @default.
- W2011833035 citedByCount "10" @default.
- W2011833035 countsByYear W20118330352013 @default.
- W2011833035 countsByYear W20118330352015 @default.
- W2011833035 countsByYear W20118330352019 @default.
- W2011833035 countsByYear W20118330352022 @default.
- W2011833035 crossrefType "journal-article" @default.
- W2011833035 hasAuthorship W2011833035A5038221128 @default.
- W2011833035 hasAuthorship W2011833035A5055441770 @default.
- W2011833035 hasAuthorship W2011833035A5060379363 @default.
- W2011833035 hasAuthorship W2011833035A5090501626 @default.
- W2011833035 hasBestOaLocation W20118330351 @default.
- W2011833035 hasConcept C134018914 @default.
- W2011833035 hasConcept C142724271 @default.
- W2011833035 hasConcept C191548132 @default.
- W2011833035 hasConcept C204232928 @default.
- W2011833035 hasConcept C2778764654 @default.
- W2011833035 hasConcept C71924100 @default.
- W2011833035 hasConcept C86803240 @default.
- W2011833035 hasConceptScore W2011833035C134018914 @default.
- W2011833035 hasConceptScore W2011833035C142724271 @default.
- W2011833035 hasConceptScore W2011833035C191548132 @default.
- W2011833035 hasConceptScore W2011833035C204232928 @default.
- W2011833035 hasConceptScore W2011833035C2778764654 @default.
- W2011833035 hasConceptScore W2011833035C71924100 @default.
- W2011833035 hasConceptScore W2011833035C86803240 @default.
- W2011833035 hasIssue "4" @default.
- W2011833035 hasLocation W20118330351 @default.
- W2011833035 hasLocation W20118330352 @default.
- W2011833035 hasOpenAccess W2011833035 @default.
- W2011833035 hasPrimaryLocation W20118330351 @default.
- W2011833035 hasRelatedWork W2007460616 @default.
- W2011833035 hasRelatedWork W2029559096 @default.
- W2011833035 hasRelatedWork W2043513838 @default.
- W2011833035 hasRelatedWork W2063480864 @default.
- W2011833035 hasRelatedWork W2109607358 @default.
- W2011833035 hasRelatedWork W2349021850 @default.
- W2011833035 hasRelatedWork W2359994504 @default.
- W2011833035 hasRelatedWork W2408693058 @default.
- W2011833035 hasRelatedWork W2416765203 @default.
- W2011833035 hasRelatedWork W2429210815 @default.
- W2011833035 hasVolume "52" @default.
- W2011833035 isParatext "false" @default.
- W2011833035 isRetracted "false" @default.
- W2011833035 magId "2011833035" @default.
- W2011833035 workType "article" @default.