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- W2011852025 abstract "Certain neurological complications appearing during the course of leukemia and related disorders are not infrequent. The occurrence of cerebral hemorrhage in the leukemias, often as a terminal event, is usually easily recognized. Involvement of the spinal epidural space by Hodgkin's disease and lymphosarcoma, resulting in paraplegia, is also a relatively common phenomenon. Focal symptomatology developing as a result of direct invasion of the brain by leukemic or lymphomatous tissue is quite uncommon; however, even this complication has been reported more frequently recently, especially in the acute leukemias managed by modern chemotherapeutic methods.<sup>1</sup> An interesting but less widely known complication of the lymphomas is a demyelinating disease of the brain, recently described by Astrom, Mancall, and Richardson.<sup>2</sup>This disease, termed progressive multifocal leukoencephalopathy, is manifested clinically by signs of diffuse brain involvement progressing rapidly, without remission, to a fatal termination within weeks or months. It has occurred predominantly in" @default.
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- W2011852025 date "1961-09-01" @default.
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- W2011852025 title "Demyelinating Disease of the Brain in Chronic Lymphatic Leukemia" @default.
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- W2011852025 doi "https://doi.org/10.1001/archneur.1961.00450150066009" @default.
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