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- W2011852486 abstract "Abstract 1.1. The diminished response to histamine in skin sites previously treated with the histamine liberator, compound 4880, was confirmed. 2.2. Pyribenzamine injected in the sites shortly before each injection of compound 4880 did not prevent depletion of histamine by the latter. 3.3. Pretreatment with Pyribenzamine prevented that degree of refractoriness apparently resulting from tissue damage by the histamine liberator. 4.4. These findings suggest that the refractoriness of the tissue to histamine response subsequent to treatment with the histamine liberator owes its action to the damaging effects of released histamine in intimate contact with the cell. 5.5. It is suggestive, but not conclusive, that the local protective action of hydrocortisone in these experiments is due mainly to histamine depletion." @default.
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- W2011852486 date "1956-05-01" @default.
- W2011852486 modified "2023-09-26" @default.
- W2011852486 title "Liberation and depletion of histamine from human skin" @default.
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- W2011852486 doi "https://doi.org/10.1016/0021-8707(56)90053-3" @default.
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