FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011861071> ?p ?o ?g. }

• W2011861071 endingPage "1961" @default.
• W2011861071 startingPage "1955" @default.
• W2011861071 abstract "Hyperfibrinogenaemia and albuminuria are cardiovascular risk factors, often coexisting in diabetic and non-diabetic people. Albuminuria in turn is associated with a compensatory albumin overproduction in non-diabetic patients. It is not known whether the presence of albuminuria in patients with type 2 diabetes mellitus is associated with greater albumin and fibrinogen production rates than in normoalbuminuric patients. SUBJECTS, MATERIALS, AND METHODS: Using leucine isotope methods, we measured fractional and absolute synthesis rates (FSR, ASR) of albumin and fibrinogen in post-absorptive type 2 diabetic patients with either normal (n=11) or increased (n=10) urinary albumin excretion.In albuminuric patients, albumin FSR (16.2+/-1.5%/day) and ASR (20.5+/-1.9 g/day) were greater (p<0.02 and p<0.05, respectively) than in normoalbuminuric patients (FSR=11.5+/-1.1%/day; ASR=15.7+/-1.2 g/day). Fibrinogen FSR was similar between patients with normal and increased albumin excretion, but concentration, the circulating pool and ASR of fibrinogen were 40 to 50% greater (p<0.035) in patients with albuminuria. Albuminuria was positively correlated with albumin ASR, with fibrinogen concentration, the fibrinogen pool and ASR, whereas albumin synthesis was inversely correlated with calculated oncotic pressure.Synthesis of albumin and fibrinogen is upregulated in type 2 diabetic patients with increased urinary albumin excretion. Albuminuria is associated with enhanced fibrinogen and albumin synthesis." @default.
• W2011861071 created "2016-06-24" @default.
• W2011861071 creator A5001757843 @default.
• W2011861071 creator A5020095053 @default.
• W2011861071 creator A5041370738 @default.
• W2011861071 creator A5061311035 @default.
• W2011861071 creator A5086993822 @default.
• W2011861071 date "2006-05-16" @default.
• W2011861071 modified "2023-10-17" @default.
• W2011861071 title "Diabetic nephropathy is associated with increased albumin and fibrinogen production in patients with type 2 diabetes" @default.
• W2011861071 cites W1819130013 @default.
• W2011861071 cites W1968485438 @default.
• W2011861071 cites W1971898954 @default.
• W2011861071 cites W1974070352 @default.
• W2011861071 cites W2001322531 @default.
• W2011861071 cites W2008795679 @default.
• W2011861071 cites W2015895756 @default.
• W2011861071 cites W2022351209 @default.
• W2011861071 cites W2029951747 @default.
• W2011861071 cites W2042219706 @default.
• W2011861071 cites W2043948526 @default.
• W2011861071 cites W2050538051 @default.
• W2011861071 cites W2052998622 @default.
• W2011861071 cites W2056518876 @default.
• W2011861071 cites W2057234872 @default.
• W2011861071 cites W2058812862 @default.
• W2011861071 cites W2067742653 @default.
• W2011861071 cites W2069557492 @default.
• W2011861071 cites W2070031467 @default.
• W2011861071 cites W2071073097 @default.
• W2011861071 cites W2078336397 @default.
• W2011861071 cites W2081143213 @default.
• W2011861071 cites W2085039467 @default.
• W2011861071 cites W2098625377 @default.
• W2011861071 cites W2106492265 @default.
• W2011861071 cites W2115812939 @default.
• W2011861071 cites W2122294444 @default.
• W2011861071 cites W2130585857 @default.
• W2011861071 cites W2132261714 @default.
• W2011861071 cites W2139203772 @default.
• W2011861071 cites W2160234571 @default.
• W2011861071 cites W2168280281 @default.
• W2011861071 cites W2183393419 @default.
• W2011861071 cites W2191797610 @default.
• W2011861071 cites W2249148211 @default.
• W2011861071 cites W2255553152 @default.
• W2011861071 cites W2324579467 @default.
• W2011861071 cites W2325569376 @default.
• W2011861071 cites W2499706994 @default.
• W2011861071 cites W2607031541 @default.
• W2011861071 cites W4300315625 @default.
• W2011861071 cites W43218661 @default.
• W2011861071 doi "https://doi.org/10.1007/s00125-006-0288-2" @default.
• W2011861071 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16703327" @default.
• W2011861071 hasPublicationYear "2006" @default.
• W2011861071 type Work @default.
• W2011861071 sameAs 2011861071 @default.
• W2011861071 citedByCount "33" @default.
• W2011861071 countsByYear W20118610712012 @default.
• W2011861071 countsByYear W20118610712013 @default.
• W2011861071 countsByYear W20118610712014 @default.
• W2011861071 countsByYear W20118610712015 @default.
• W2011861071 countsByYear W20118610712016 @default.
• W2011861071 countsByYear W20118610712017 @default.
• W2011861071 countsByYear W20118610712018 @default.
• W2011861071 countsByYear W20118610712019 @default.
• W2011861071 countsByYear W20118610712020 @default.
• W2011861071 countsByYear W20118610712021 @default.
• W2011861071 countsByYear W20118610712022 @default.
• W2011861071 countsByYear W20118610712023 @default.
• W2011861071 crossrefType "journal-article" @default.
• W2011861071 hasAuthorship W2011861071A5001757843 @default.
• W2011861071 hasAuthorship W2011861071A5020095053 @default.
• W2011861071 hasAuthorship W2011861071A5041370738 @default.
• W2011861071 hasAuthorship W2011861071A5061311035 @default.
• W2011861071 hasAuthorship W2011861071A5086993822 @default.
• W2011861071 hasBestOaLocation W20118610711 @default.
• W2011861071 hasConcept C10146269 @default.
• W2011861071 hasConcept C126322002 @default.
• W2011861071 hasConcept C134018914 @default.
• W2011861071 hasConcept C165616093 @default.
• W2011861071 hasConcept C2776125364 @default.
• W2011861071 hasConcept C2776174234 @default.
• W2011861071 hasConcept C2779036427 @default.
• W2011861071 hasConcept C2779922275 @default.
• W2011861071 hasConcept C2781203188 @default.
• W2011861071 hasConcept C555293320 @default.
• W2011861071 hasConcept C71924100 @default.
• W2011861071 hasConceptScore W2011861071C10146269 @default.
• W2011861071 hasConceptScore W2011861071C126322002 @default.
• W2011861071 hasConceptScore W2011861071C134018914 @default.
• W2011861071 hasConceptScore W2011861071C165616093 @default.
• W2011861071 hasConceptScore W2011861071C2776125364 @default.
• W2011861071 hasConceptScore W2011861071C2776174234 @default.
• W2011861071 hasConceptScore W2011861071C2779036427 @default.
• W2011861071 hasConceptScore W2011861071C2779922275 @default.
• W2011861071 hasConceptScore W2011861071C2781203188 @default.
• W2011861071 hasConceptScore W2011861071C555293320 @default.

• next