FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011869196> ?p ?o ?g. }

• W2011869196 endingPage "89" @default.
• W2011869196 startingPage "81" @default.
• W2011869196 abstract "In contrast to the “validation” of short-term in vitro genotoxicity assays by concordance with the rodent cancer bioassay, the present report describes the multiple replication of 4 short-term tests with V79 cells (micronucleus assay, MN; sister-chromatid exchange, SCE; ouabain resistance, OUR; and thioguanine resistance, TGR) within the same assay system following exposure to each of two genotoxins, ethyl methanesulfonate (direct acting) and 7,12-dimethylbenz[a]anthracene (indirect acting). Reproducibility, proportion of genotoxins correctly identified, and proportion of non-genotoxins correctly identified by each test were each determined statistically. Decision rules were formulated to declare a positive response in each assay, and overall accuracy of each was determined. Statistical analysis of the data, obtained under standardized test conditions, showed that for these two chemicals SCE identified 100% of genotoxins and 86% of non-genotoxins, with overall accuracy of prediction of 93%; TGR identified 98% of genotoxins and 74% of non-genotoxins, with overall accuracy of 86%; MN identified 78% of genotoxins and 84% of non-genotoxins, with overall accuracy of 81%; while OUR indicated 100% of genotoxins, but only 50% of non-genotoxins, and only 76% overall accuracy. The results suggested that the best overall accuracy of classification with the V79 assay system could be achieved by measurement of SCE in combination with thioguanine resistance." @default.
• W2011869196 created "2016-06-24" @default.
• W2011869196 creator A5006821104 @default.
• W2011869196 creator A5018647190 @default.
• W2011869196 creator A5036759427 @default.
• W2011869196 creator A5064396658 @default.
• W2011869196 date "1990-04-01" @default.
• W2011869196 modified "2023-09-26" @default.
• W2011869196 title "A statistical evaluation of the reproducibility of micronucleus, sister-chromatid exchange, thioguanine-resistance and ouabain-resistance assays in V79 cells exposed to ethyl methanesulfonate and 7,12-dimethylbenz[a]anthracene" @default.
• W2011869196 cites W116115124 @default.
• W2011869196 cites W1965724734 @default.
• W2011869196 cites W1969294047 @default.
• W2011869196 cites W1978239142 @default.
• W2011869196 cites W1978305149 @default.
• W2011869196 cites W1982970565 @default.
• W2011869196 cites W2002400756 @default.
• W2011869196 cites W2006984368 @default.
• W2011869196 cites W2025338070 @default.
• W2011869196 cites W2041491258 @default.
• W2011869196 cites W2043579193 @default.
• W2011869196 cites W2052666933 @default.
• W2011869196 cites W2055499537 @default.
• W2011869196 cites W2061793997 @default.
• W2011869196 cites W2064637938 @default.
• W2011869196 cites W2073997322 @default.
• W2011869196 cites W2078330627 @default.
• W2011869196 cites W2080049100 @default.
• W2011869196 cites W2090805400 @default.
• W2011869196 cites W2091188789 @default.
• W2011869196 cites W2095534702 @default.
• W2011869196 cites W2117856769 @default.
• W2011869196 cites W2120722284 @default.
• W2011869196 cites W2131418325 @default.
• W2011869196 cites W2170715830 @default.
• W2011869196 cites W2460847144 @default.
• W2011869196 cites W3141974803 @default.
• W2011869196 doi "https://doi.org/10.1016/0165-1161(90)90034-l" @default.
• W2011869196 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2109193" @default.
• W2011869196 hasPublicationYear "1990" @default.
• W2011869196 type Work @default.
• W2011869196 sameAs 2011869196 @default.
• W2011869196 citedByCount "4" @default.
• W2011869196 crossrefType "journal-article" @default.
• W2011869196 hasAuthorship W2011869196A5006821104 @default.
• W2011869196 hasAuthorship W2011869196A5018647190 @default.
• W2011869196 hasAuthorship W2011869196A5036759427 @default.
• W2011869196 hasAuthorship W2011869196A5064396658 @default.
• W2011869196 hasConcept C104317684 @default.
• W2011869196 hasConcept C104488531 @default.
• W2011869196 hasConcept C153911025 @default.
• W2011869196 hasConcept C178790620 @default.
• W2011869196 hasConcept C185592680 @default.
• W2011869196 hasConcept C202751555 @default.
• W2011869196 hasConcept C2778959862 @default.
• W2011869196 hasConcept C2779071816 @default.
• W2011869196 hasConcept C29730261 @default.
• W2011869196 hasConcept C30481170 @default.
• W2011869196 hasConcept C33070731 @default.
• W2011869196 hasConcept C36681516 @default.
• W2011869196 hasConcept C45080847 @default.
• W2011869196 hasConcept C54355233 @default.
• W2011869196 hasConcept C55493867 @default.
• W2011869196 hasConcept C8502773 @default.
• W2011869196 hasConcept C86803240 @default.
• W2011869196 hasConceptScore W2011869196C104317684 @default.
• W2011869196 hasConceptScore W2011869196C104488531 @default.
• W2011869196 hasConceptScore W2011869196C153911025 @default.
• W2011869196 hasConceptScore W2011869196C178790620 @default.
• W2011869196 hasConceptScore W2011869196C185592680 @default.
• W2011869196 hasConceptScore W2011869196C202751555 @default.
• W2011869196 hasConceptScore W2011869196C2778959862 @default.
• W2011869196 hasConceptScore W2011869196C2779071816 @default.
• W2011869196 hasConceptScore W2011869196C29730261 @default.
• W2011869196 hasConceptScore W2011869196C30481170 @default.
• W2011869196 hasConceptScore W2011869196C33070731 @default.
• W2011869196 hasConceptScore W2011869196C36681516 @default.
• W2011869196 hasConceptScore W2011869196C45080847 @default.
• W2011869196 hasConceptScore W2011869196C54355233 @default.
• W2011869196 hasConceptScore W2011869196C55493867 @default.
• W2011869196 hasConceptScore W2011869196C8502773 @default.
• W2011869196 hasConceptScore W2011869196C86803240 @default.
• W2011869196 hasIssue "2" @default.
• W2011869196 hasLocation W20118691961 @default.
• W2011869196 hasLocation W20118691962 @default.
• W2011869196 hasOpenAccess W2011869196 @default.
• W2011869196 hasPrimaryLocation W20118691961 @default.
• W2011869196 hasRelatedWork W1589822950 @default.
• W2011869196 hasRelatedWork W1974756054 @default.
• W2011869196 hasRelatedWork W1977089134 @default.
• W2011869196 hasRelatedWork W1993106774 @default.
• W2011869196 hasRelatedWork W2026348885 @default.
• W2011869196 hasRelatedWork W2028385361 @default.
• W2011869196 hasRelatedWork W2058674221 @default.
• W2011869196 hasRelatedWork W2078782305 @default.
• W2011869196 hasRelatedWork W2080606236 @default.
• W2011869196 hasRelatedWork W9421691 @default.
• W2011869196 hasVolume "234" @default.
• W2011869196 isParatext "false" @default.

• next