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- W2011876586 abstract "The effects of supplemental albumin infusion on serum protein homeostasis were studied in 94 seriously injured patients who received an average of 14.4 transfusions, 9.2 L electrolyte solution, and 829 ml fresh frozen plasma before and during operation. Based on randomization, 46 patients received an average of 31 gm albumin during operation followed by 150 gm/day for 5 days; 48 patients received no albumin. Supplemental albumin caused a significant (p=<0.05) increase in total serum protein and albumin concentrations. In contrast, supplemental albumin caused a significant decrease in α1 globulin, α2 globulin, β globulin, γ globulin, and fibrinogen levels. The prothrombin time used as index of prothrombin concentration was significantly prolonged in albumin patients. These changes, not previously documented, need further evaluation to determine clinical significance." @default.
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- W2011876586 date "1980-01-01" @default.
- W2011876586 modified "2023-09-30" @default.
- W2011876586 title "Differential Serum Protein Changes Following Supplemental Albumin Resuscitation for Hypovolemic Shock" @default.
- W2011876586 doi "https://doi.org/10.1097/00005373-198001000-00006" @default.
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