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- W2011900577 abstract "A male patient with mixed gonadal dysgenesis, involving a streak gonad on the right and a histologically normal testis in the left, was found to have a 45,X/46,X,dic(Yp) chromosome constitution on peripheral blood cultures. Fibroblasts grown from both gonads showed the normal testicular tissue to have e 45,X/46,X,dic(Yp), whereas the cells from the streak gonad were all 45,X. The structure of the dic(Yp) chromosome was confirmed using non-isotopic in situ hybridization with Y centromere and Yp specific probes. On hormonal stimulation, testosterone levels rose by 50%. The normal testis was left in situ, but close follow up will be required in view of the malignant potential." @default.
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- W2011900577 date "2008-06-28" @default.
- W2011900577 modified "2023-09-23" @default.
- W2011900577 title "Mixed gonadal dysgenesis and cell line differentiation. Case presentation and literature review" @default.
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- W2011900577 doi "https://doi.org/10.1111/j.1399-0004.1994.tb04167.x" @default.
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