FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2011931614> ?p ?o ?g. }

• W2011931614 endingPage "1550" @default.
• W2011931614 startingPage "1543" @default.
• W2011931614 abstract "Articular cartilage is a hydrated soft tissue composed of negatively charged proteoglycans fixed within a collagen matrix. This charge gradient causes the tissue to imbibe water and swell, creating a net osmotic pressure that enhances the tissue’s ability to bear load. In this study we designed and utilized an apparatus for directly measuring the osmotic pressure of chondroitin sulfate, the primary glycosaminoglycan found in articular cartilage, in solution with varying bathing ionic strength (0.015 M, 0.15 M, 0.5 M, 1 M, and 2 M NaCl) at room temperature. The osmotic pressure (π) was found to increase nonlinearly with increasing chondroitin sulfate concentration and decreasing NaCl ionic bath environment. Above 1 M NaCl, π changes negligibly with further increases in salt concentration, suggesting that Donnan osmotic pressure is negligible above this threshold, and the resulting pressure is attributed to configurational entropy. Results of the current study were also used to estimate the contribution of osmotic pressure to the stiffness of cartilage based on theoretical and experimental considerations. Our findings indicate that the osmotic pressure resulting from configurational entropy is much smaller in cartilage (based on an earlier study on bovine articular cartilage) than in free solution. The rate of change of osmotic pressure with compressive strain is found to contribute approximately one-third of the compressive modulus (HAeff) of cartilage (Π∼HAeff/3), with the balance contributed by the intrinsic structural modulus of the solid matrix (i.e., HA∼2HAeff/3). A strong dependence of this intrinsic modulus on salt concentration was found; therefore, it appears that proteoglycans contribute structurally to the magnitude of HA, in a manner independent of osmotic pressure." @default.
• W2011931614 created "2016-06-24" @default.
• W2011931614 creator A5010048130 @default.
• W2011931614 creator A5022022053 @default.
• W2011931614 creator A5041219159 @default.
• W2011931614 creator A5088655754 @default.
• W2011931614 date "2005-09-01" @default.
• W2011931614 modified "2023-10-06" @default.
• W2011931614 title "Direct Measurement of Osmotic Pressure of Glycosaminoglycan Solutions by Membrane Osmometry at Room Temperature" @default.
• W2011931614 cites W127220886 @default.
• W2011931614 cites W1966686938 @default.
• W2011931614 cites W1968404177 @default.
• W2011931614 cites W1972325592 @default.
• W2011931614 cites W1979837737 @default.
• W2011931614 cites W1987135075 @default.
• W2011931614 cites W1992238022 @default.
• W2011931614 cites W2023242464 @default.
• W2011931614 cites W2033620253 @default.
• W2011931614 cites W2037374077 @default.
• W2011931614 cites W2049656644 @default.
• W2011931614 cites W2055884129 @default.
• W2011931614 cites W2060854470 @default.
• W2011931614 cites W2062155239 @default.
• W2011931614 cites W2064791767 @default.
• W2011931614 cites W2086027952 @default.
• W2011931614 cites W2095964234 @default.
• W2011931614 cites W2116178713 @default.
• W2011931614 cites W2152637989 @default.
• W2011931614 cites W2281112318 @default.
• W2011931614 doi "https://doi.org/10.1529/biophysj.104.057315" @default.
• W2011931614 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1366659" @default.
• W2011931614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15980166" @default.
• W2011931614 hasPublicationYear "2005" @default.
• W2011931614 type Work @default.
• W2011931614 sameAs 2011931614 @default.
• W2011931614 citedByCount "100" @default.
• W2011931614 countsByYear W20119316142012 @default.
• W2011931614 countsByYear W20119316142013 @default.
• W2011931614 countsByYear W20119316142014 @default.
• W2011931614 countsByYear W20119316142015 @default.
• W2011931614 countsByYear W20119316142016 @default.
• W2011931614 countsByYear W20119316142017 @default.
• W2011931614 countsByYear W20119316142018 @default.
• W2011931614 countsByYear W20119316142019 @default.
• W2011931614 countsByYear W20119316142020 @default.
• W2011931614 countsByYear W20119316142021 @default.
• W2011931614 countsByYear W20119316142022 @default.
• W2011931614 countsByYear W20119316142023 @default.
• W2011931614 crossrefType "journal-article" @default.
• W2011931614 hasAuthorship W2011931614A5010048130 @default.
• W2011931614 hasAuthorship W2011931614A5022022053 @default.
• W2011931614 hasAuthorship W2011931614A5041219159 @default.
• W2011931614 hasAuthorship W2011931614A5088655754 @default.
• W2011931614 hasBestOaLocation W20119316141 @default.
• W2011931614 hasConcept C105702510 @default.
• W2011931614 hasConcept C113196181 @default.
• W2011931614 hasConcept C12554922 @default.
• W2011931614 hasConcept C150193269 @default.
• W2011931614 hasConcept C153074725 @default.
• W2011931614 hasConcept C159985019 @default.
• W2011931614 hasConcept C178790620 @default.
• W2011931614 hasConcept C184651966 @default.
• W2011931614 hasConcept C185592680 @default.
• W2011931614 hasConcept C187428577 @default.
• W2011931614 hasConcept C192562407 @default.
• W2011931614 hasConcept C2779553658 @default.
• W2011931614 hasConcept C2780550940 @default.
• W2011931614 hasConcept C41625074 @default.
• W2011931614 hasConcept C43486711 @default.
• W2011931614 hasConcept C43617362 @default.
• W2011931614 hasConcept C55493867 @default.
• W2011931614 hasConcept C71924100 @default.
• W2011931614 hasConcept C86803240 @default.
• W2011931614 hasConcept C91973860 @default.
• W2011931614 hasConcept C9603476 @default.
• W2011931614 hasConceptScore W2011931614C105702510 @default.
• W2011931614 hasConceptScore W2011931614C113196181 @default.
• W2011931614 hasConceptScore W2011931614C12554922 @default.
• W2011931614 hasConceptScore W2011931614C150193269 @default.
• W2011931614 hasConceptScore W2011931614C153074725 @default.
• W2011931614 hasConceptScore W2011931614C159985019 @default.
• W2011931614 hasConceptScore W2011931614C178790620 @default.
• W2011931614 hasConceptScore W2011931614C184651966 @default.
• W2011931614 hasConceptScore W2011931614C185592680 @default.
• W2011931614 hasConceptScore W2011931614C187428577 @default.
• W2011931614 hasConceptScore W2011931614C192562407 @default.
• W2011931614 hasConceptScore W2011931614C2779553658 @default.
• W2011931614 hasConceptScore W2011931614C2780550940 @default.
• W2011931614 hasConceptScore W2011931614C41625074 @default.
• W2011931614 hasConceptScore W2011931614C43486711 @default.
• W2011931614 hasConceptScore W2011931614C43617362 @default.
• W2011931614 hasConceptScore W2011931614C55493867 @default.
• W2011931614 hasConceptScore W2011931614C71924100 @default.
• W2011931614 hasConceptScore W2011931614C86803240 @default.
• W2011931614 hasConceptScore W2011931614C91973860 @default.
• W2011931614 hasConceptScore W2011931614C9603476 @default.
• W2011931614 hasIssue "3" @default.
• W2011931614 hasLocation W20119316141 @default.

• next