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• W2011969971 startingPage "7341" @default.
• W2011969971 abstract "Replication of the 14-micrometer linear Paramecium mitochondrial DNA is initiated by a crosslinking of the duplex strands at the initiation end of the molecule. As a consequence of the crosslink, a head-to-head dimer molecule, or palindrome, is a replicative intermediate. The central region of the dimer molecules of two species was cloned and sequenced, In the distal regions, the sequence is palindromic as expected; however, in the central region, there is a nonpalindromic sequence that is rich in A + T and contains direct tandem repeats. It is proposed that the nonpalindromic sequence constitutes the crosslink. Implications for the replication scheme are discussed. The model is unlike any other for a linear DNA." @default.
• W2011969971 created "2016-06-24" @default.
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• W2011969971 date "1981-12-01" @default.
• W2011969971 modified "2023-09-25" @default.
• W2011969971 title "Replication of linear mitochondrial DNA from Paramecium: sequence and structure of the initiation-end crosslink." @default.
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• W2011969971 doi "https://doi.org/10.1073/pnas.78.12.7341" @default.
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