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- W2011984023 abstract "To compare low-molecular-weight (LMW) heparin plus low-dose aspirin with intravenous immunoglobulin (IVIG) in the treatment of antiphospholipid antibody syndrome in women with recurrent spontaneous abortions before 10 weeks of gestation.This prospective, multicenter trial conducted between 2002 and 2006 included 85 patients aged 18–39 years. The women were allocated randomly to receive LMW heparin plus low-dose aspirin, or IVIG. Data were compared using the t test and Fisher exact test.The women treated with LMW heparin plus low-dose aspirin had a higher rate of live births than those treated with IVIG (P = 0.003). Of those who completed the study, 29/40 (72.5%) and 15/38 (39.5%), respectively, had live births. Intent-to-treat analysis revealed a significant difference between the 2 groups (OR 1.802; 95%CI, 1.14–2.84; P = 0.007).LMW heparin plus low-dose aspirin resulted in a higher live birth rate than IVIG in the treatment of antiphospholipid antibody syndrome in women with recurrent abortion." @default.
- W2011984023 created "2016-06-24" @default.
- W2011984023 creator A5039304063 @default.
- W2011984023 date "1989-08-01" @default.
- W2011984023 modified "2023-10-07" @default.
- W2011984023 title "Pregnancy-associated immunological disorders" @default.
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- W2011984023 doi "https://doi.org/10.1016/0952-7915(89)90010-1" @default.
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