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- W2011991446 abstract "Abstract Mild substitution reactions of acetals with carbon nucleophiles via the pyridinium‐type salts generated by the treatment of acetals with TESOTf‐2,4,6‐collidine or 2,2′‐bipyridyl have been developed. Various carbon nucleophiles, such as organocuprates, silyl enol ethers, enamines, etc., reacted with the pyridinium‐type salts to give the corresponding substituted products in good yields. The reactions proceeded under very mild conditions (non‐acidic conditions) and thus acid‐sensitive functional groups can be tolerated during the reaction. In addition, only an acetal can form the pyridinium‐type salt and react with nucleophiles in the presence of a ketal. This unusual selectivity is in contrast to general methods conducted under acidic conditions." @default.
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- W2011991446 date "2011-12-12" @default.
- W2011991446 modified "2023-10-18" @default.
- W2011991446 title "Reaction of Acetals with Various Carbon Nucleophiles under Non-Acidic Conditions: CC Bond Formation via a Pyridinium-Type Salt" @default.
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- W2011991446 doi "https://doi.org/10.1002/asia.201100812" @default.
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