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- W2012004290 abstract "A 66-year-old male patient has undergone several percutaneous coronary interventions (PCIs) for ischemic heart disease in the past and has been on dialysis due to diabetic nephritis since last year. The ischemia-induced exacerbation of cardiac function and ischemic mitral regurgitation (MR) provoked by ventricular remodeling have progressed, and the patient has been treated for ischemic heart failure with an oral ACE inhibitor and an oral β-adrenergic blocking agent. Recently, however, the patient has repeated hospitalizations due to volume overload. The present hospitalization was due to the aggravation of chronic heart failure, treatment with dobutamine was initiated, and PCI and cardiac resynchronization therapy (CRT) were conducted to improve cardiac function. The patient presents highly risky MR and has been excluded from surgical indication. Heart transplantation is not indicated for the patient because of his age. A number of options in therapeutic drugs for heart failure have become available in recent years, and sorts of therapeutic means have been reported. However, it is difficult to figure out pharmacokinetics in blood when treating patients with heart failure who are on maintenance dialysis, and a limited number of drugs that can be used safely are available. We have encountered a patient with severe heart failure who has been on maintenance dialysis and hereby report on the patient together with discussion about therapeutic strategies." @default.
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- W2012004290 date "2008-09-01" @default.
- W2012004290 modified "2023-09-26" @default.
- W2012004290 title "A patient on maintenance dialysis who has repeated hospitalizations due to severe heart failure provoked by ischemic mitral regurgitation" @default.
- W2012004290 doi "https://doi.org/10.1016/j.cardfail.2008.07.222" @default.
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