Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012007342> ?p ?o ?g. }
- W2012007342 endingPage "818" @default.
- W2012007342 startingPage "814" @default.
- W2012007342 abstract "Amelogenins are a group of heterogenous proteins first identified in developing tooth enamel and reported to be present in odontoblasts. The objective of this study was to elucidate the expression and function of amelogenins in the human dentin-pulp complex. Developing human tooth buds were immunostained for amelogenin, and mRNA was detected by in situ hybridization. The effects of recombinant amelogenins on pulp and papilla cell proliferation were measured by Brd U immunoassay, and differentiation was monitored by alkaline phosphatase expression. Amelogenin protein was found in the forming dentin matrix, and amelogenin mRNA was localized in the dentin, presumably in the odontoblast processes. Proliferation of papilla cells was enhanced by recombinant human amelogenin rH72 (LRAP+ exon 4), while pulp cells responded to both rH72 and rH58 (LRAP), with no effect by rH174. These studies suggest that odontoblasts actively synthesize and secrete amelogenin protein during human tooth development, and that low-molecular-weight amelogenins can enhance pulp cell proliferation." @default.
- W2012007342 created "2016-06-24" @default.
- W2012007342 creator A5009775989 @default.
- W2012007342 creator A5015086246 @default.
- W2012007342 creator A5016056002 @default.
- W2012007342 creator A5023166244 @default.
- W2012007342 creator A5032786179 @default.
- W2012007342 creator A5069253305 @default.
- W2012007342 creator A5072929035 @default.
- W2012007342 date "2006-09-01" @default.
- W2012007342 modified "2023-10-03" @default.
- W2012007342 title "Amelogenins in Human Developing and Mature Dental Pulp" @default.
- W2012007342 cites W1492256206 @default.
- W2012007342 cites W1976235566 @default.
- W2012007342 cites W1978212420 @default.
- W2012007342 cites W1983580095 @default.
- W2012007342 cites W1992068568 @default.
- W2012007342 cites W2006876029 @default.
- W2012007342 cites W2008343847 @default.
- W2012007342 cites W2010420775 @default.
- W2012007342 cites W2019423191 @default.
- W2012007342 cites W2029665254 @default.
- W2012007342 cites W2036433722 @default.
- W2012007342 cites W2036819945 @default.
- W2012007342 cites W2053958155 @default.
- W2012007342 cites W2063237398 @default.
- W2012007342 cites W2067612225 @default.
- W2012007342 cites W2068741867 @default.
- W2012007342 cites W2078738113 @default.
- W2012007342 cites W2085612317 @default.
- W2012007342 cites W2085847863 @default.
- W2012007342 cites W2090205800 @default.
- W2012007342 cites W2093913964 @default.
- W2012007342 cites W2094443331 @default.
- W2012007342 cites W2094935991 @default.
- W2012007342 cites W2103957439 @default.
- W2012007342 cites W2104748476 @default.
- W2012007342 cites W2121987287 @default.
- W2012007342 cites W2130516299 @default.
- W2012007342 cites W2155609574 @default.
- W2012007342 cites W2163404165 @default.
- W2012007342 doi "https://doi.org/10.1177/154405910608500907" @default.
- W2012007342 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2243219" @default.
- W2012007342 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16931863" @default.
- W2012007342 hasPublicationYear "2006" @default.
- W2012007342 type Work @default.
- W2012007342 sameAs 2012007342 @default.
- W2012007342 citedByCount "39" @default.
- W2012007342 countsByYear W20120073422012 @default.
- W2012007342 countsByYear W20120073422013 @default.
- W2012007342 countsByYear W20120073422014 @default.
- W2012007342 countsByYear W20120073422015 @default.
- W2012007342 countsByYear W20120073422016 @default.
- W2012007342 countsByYear W20120073422017 @default.
- W2012007342 countsByYear W20120073422018 @default.
- W2012007342 countsByYear W20120073422020 @default.
- W2012007342 countsByYear W20120073422021 @default.
- W2012007342 countsByYear W20120073422022 @default.
- W2012007342 countsByYear W20120073422023 @default.
- W2012007342 crossrefType "journal-article" @default.
- W2012007342 hasAuthorship W2012007342A5009775989 @default.
- W2012007342 hasAuthorship W2012007342A5015086246 @default.
- W2012007342 hasAuthorship W2012007342A5016056002 @default.
- W2012007342 hasAuthorship W2012007342A5023166244 @default.
- W2012007342 hasAuthorship W2012007342A5032786179 @default.
- W2012007342 hasAuthorship W2012007342A5069253305 @default.
- W2012007342 hasAuthorship W2012007342A5072929035 @default.
- W2012007342 hasBestOaLocation W20120073422 @default.
- W2012007342 hasConcept C104317684 @default.
- W2012007342 hasConcept C105580179 @default.
- W2012007342 hasConcept C106434640 @default.
- W2012007342 hasConcept C156887251 @default.
- W2012007342 hasConcept C185592680 @default.
- W2012007342 hasConcept C188442228 @default.
- W2012007342 hasConcept C199343813 @default.
- W2012007342 hasConcept C2520015 @default.
- W2012007342 hasConcept C2779263046 @default.
- W2012007342 hasConcept C55493867 @default.
- W2012007342 hasConcept C69103154 @default.
- W2012007342 hasConcept C71924100 @default.
- W2012007342 hasConcept C72041822 @default.
- W2012007342 hasConcept C81439078 @default.
- W2012007342 hasConcept C86803240 @default.
- W2012007342 hasConcept C95444343 @default.
- W2012007342 hasConceptScore W2012007342C104317684 @default.
- W2012007342 hasConceptScore W2012007342C105580179 @default.
- W2012007342 hasConceptScore W2012007342C106434640 @default.
- W2012007342 hasConceptScore W2012007342C156887251 @default.
- W2012007342 hasConceptScore W2012007342C185592680 @default.
- W2012007342 hasConceptScore W2012007342C188442228 @default.
- W2012007342 hasConceptScore W2012007342C199343813 @default.
- W2012007342 hasConceptScore W2012007342C2520015 @default.
- W2012007342 hasConceptScore W2012007342C2779263046 @default.
- W2012007342 hasConceptScore W2012007342C55493867 @default.
- W2012007342 hasConceptScore W2012007342C69103154 @default.
- W2012007342 hasConceptScore W2012007342C71924100 @default.
- W2012007342 hasConceptScore W2012007342C72041822 @default.
- W2012007342 hasConceptScore W2012007342C81439078 @default.