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- W2012021753 abstract "Small intestinal Paneth cells secrete a-defensin peptides, termed cryptdins (Crps) in mice, into the intestinal lumen, where they confer immunity to oral infections and define the composition of the ileal microbiota. In these studies, facultative bacteria maintained under aerobic or anaerobic conditions displayed differential sensitivities to mouse a-defensins under in vitro assay conditions. Regardless of oxygenation, Crps 2 and 3 had robust and similar bactericidal activities against S. typhimurium and S. flexneri, but Crp4 activity against S. flexneri was attenuated in the absence of oxygen. Anaerobic bacteria varied in their susceptibility to Crps 2-4, with Crp4 showing less activity than Crps 2 and 3 against Enterococcus faecalis, and Bacteroides fragilis in anaerobic assays, but Fusobacterium necrophorum was killed only by Crp4 and not by Crps 2 and 3. The influence of anaerobiosis in modulating Crp bactericidal activities in vitro suggests that a-defensin effects on the enteric microbiota may be subject to regulation by local oxygen tension." @default.
- W2012021753 created "2016-06-24" @default.
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- W2012021753 date "2014-10-17" @default.
- W2012021753 modified "2023-09-29" @default.
- W2012021753 title "Differential Susceptibility of Bacteria to Mouse Paneth Cell a-Defensins under Anaerobic Conditions" @default.
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- W2012021753 cites W1987836935 @default.
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- W2012021753 cites W2003112779 @default.
- W2012021753 cites W2004731415 @default.
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- W2012021753 doi "https://doi.org/10.3390/antibiotics3040493" @default.
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