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- W2012026384 abstract "It has been concluded recently that if a projection from the marginal zone to the ventral posterior lateral (VPL) nucleus exists, it is sparse. Given the importance of the marginal zone in nociception, this conclusion has raised doubts about the significance of the role of the ventrobasal complex in nociception. We have reexamined this projection using injections of the retrograde tracer, cholera toxin subunit B, into one side of the lateral thalamus in macaque monkeys. The injections were confined to the ventrobasal complex (with minimal spread to adjacent nuclei that do not receive spinal projections) in two animals. Many retrogradely labeled neurons were found in lamina I (as well as in lamina V) of the contralateral spinal and medullary dorsal horn. The results are consistent with the view that neurons in the marginal zone contribute prominently to the spinothalamic and trigeminothalamic projections to the VPL and ventral posterior medial (VPM) nuclei. This pathway is likely to be important for the sensory-discriminative processing of nociceptive information with respect to the location and intensity of painful stimuli." @default.
- W2012026384 created "2016-06-24" @default.
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- W2012026384 date "2001-05-01" @default.
- W2012026384 modified "2023-10-17" @default.
- W2012026384 title "Projections from the marginal zone and deep dorsal horn to the ventrobasal nuclei of the primate thalamus" @default.
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- W2012026384 doi "https://doi.org/10.1016/s0304-3959(01)00268-8" @default.
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