Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012037611> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2012037611 endingPage "247" @default.
- W2012037611 startingPage "240" @default.
- W2012037611 abstract "Introduction: Streptococcus sobrinus exhibits marked dextran-dependent aggregation mediated by glucan-binding proteins (GBPs). In contrast to Streptococcus mutans, in which the gbpC gene responsible for dextran-dependent aggregation of this organism has been characterized, genes encoding the S. sobrinus GBPs have not yet been identified. Methods: Recently, we identified the gbpC gene homologue from Streptococcus macacae using polymerase chain reaction primers based on the conserved regions of the gbpC sequence exhibiting intraspecies variations. This method was applied to amplify a S. sobrinus homologue. Results: Unexpectedly, two gbpC gene homologues were identified in S. sobrinus strain 100-4. One homologue, named gbpC, was more similar to the S. mutans gbpC gene than the other and was approximately half the molecular size of its homologue with similar regions interrupted by several non-similar stretches. However, the dextran-binding activity of the protein expressed from gbpC in Escherichia coli was not detected in contrast to the other homologue, a protein designated as Dbl, expressing this activity. The gbpC gene was shown to be intact on the chromosome of strain OMZ176, which does not exhibit dextran-dependent aggregation, while the dbl gene of this strain contained a single adenine nucleotide insertion at approximately one-third the distance from the 5′-end. The insertion mutation in the dbl gene resulted in translation of a premature protein missing its LPXTG sequence signature sequence of the wall-anchored proteins. Conclusion: These results suggest that the dbl gene is very likely responsible for S. sobrinus dextran-dependent aggregation." @default.
- W2012037611 created "2016-06-24" @default.
- W2012037611 creator A5013263666 @default.
- W2012037611 creator A5037747824 @default.
- W2012037611 creator A5039957890 @default.
- W2012037611 creator A5084896353 @default.
- W2012037611 creator A5086752971 @default.
- W2012037611 date "2007-08-01" @default.
- W2012037611 modified "2023-09-26" @default.
- W2012037611 title "One of two gbpC gene homologues is involved in dextran-dependent aggregation of Streptococcus sobrinus" @default.
- W2012037611 cites W1536750901 @default.
- W2012037611 cites W1848722042 @default.
- W2012037611 cites W1910698696 @default.
- W2012037611 cites W1979179686 @default.
- W2012037611 cites W1981777358 @default.
- W2012037611 cites W2009658014 @default.
- W2012037611 cites W2026299326 @default.
- W2012037611 cites W2032557107 @default.
- W2012037611 cites W2035860799 @default.
- W2012037611 cites W2098098638 @default.
- W2012037611 cites W2105952171 @default.
- W2012037611 cites W2115127030 @default.
- W2012037611 cites W2120280700 @default.
- W2012037611 cites W2128618257 @default.
- W2012037611 cites W2133887597 @default.
- W2012037611 cites W2142305747 @default.
- W2012037611 cites W2144134342 @default.
- W2012037611 cites W2146052711 @default.
- W2012037611 cites W2148216185 @default.
- W2012037611 cites W2151493675 @default.
- W2012037611 cites W2167820176 @default.
- W2012037611 cites W2171091522 @default.
- W2012037611 cites W4231311323 @default.
- W2012037611 cites W4242170471 @default.
- W2012037611 cites W68626739 @default.
- W2012037611 doi "https://doi.org/10.1111/j.1399-302x.2006.00347.x" @default.
- W2012037611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17600535" @default.
- W2012037611 hasPublicationYear "2007" @default.
- W2012037611 type Work @default.
- W2012037611 sameAs 2012037611 @default.
- W2012037611 citedByCount "7" @default.
- W2012037611 countsByYear W20120376112012 @default.
- W2012037611 countsByYear W20120376112015 @default.
- W2012037611 countsByYear W20120376112017 @default.
- W2012037611 countsByYear W20120376112020 @default.
- W2012037611 crossrefType "journal-article" @default.
- W2012037611 hasAuthorship W2012037611A5013263666 @default.
- W2012037611 hasAuthorship W2012037611A5037747824 @default.
- W2012037611 hasAuthorship W2012037611A5039957890 @default.
- W2012037611 hasAuthorship W2012037611A5084896353 @default.
- W2012037611 hasAuthorship W2012037611A5086752971 @default.
- W2012037611 hasBestOaLocation W20120376112 @default.
- W2012037611 hasConcept C104317684 @default.
- W2012037611 hasConcept C153911025 @default.
- W2012037611 hasConcept C2778430296 @default.
- W2012037611 hasConcept C2779958046 @default.
- W2012037611 hasConcept C523546767 @default.
- W2012037611 hasConcept C54355233 @default.
- W2012037611 hasConcept C55493867 @default.
- W2012037611 hasConcept C84148353 @default.
- W2012037611 hasConcept C86803240 @default.
- W2012037611 hasConcept C89423630 @default.
- W2012037611 hasConceptScore W2012037611C104317684 @default.
- W2012037611 hasConceptScore W2012037611C153911025 @default.
- W2012037611 hasConceptScore W2012037611C2778430296 @default.
- W2012037611 hasConceptScore W2012037611C2779958046 @default.
- W2012037611 hasConceptScore W2012037611C523546767 @default.
- W2012037611 hasConceptScore W2012037611C54355233 @default.
- W2012037611 hasConceptScore W2012037611C55493867 @default.
- W2012037611 hasConceptScore W2012037611C84148353 @default.
- W2012037611 hasConceptScore W2012037611C86803240 @default.
- W2012037611 hasConceptScore W2012037611C89423630 @default.
- W2012037611 hasIssue "4" @default.
- W2012037611 hasLocation W20120376111 @default.
- W2012037611 hasLocation W20120376112 @default.
- W2012037611 hasLocation W20120376113 @default.
- W2012037611 hasOpenAccess W2012037611 @default.
- W2012037611 hasPrimaryLocation W20120376111 @default.
- W2012037611 hasRelatedWork W1483059914 @default.
- W2012037611 hasRelatedWork W1979179686 @default.
- W2012037611 hasRelatedWork W1991725229 @default.
- W2012037611 hasRelatedWork W2012037611 @default.
- W2012037611 hasRelatedWork W2029376645 @default.
- W2012037611 hasRelatedWork W2037494728 @default.
- W2012037611 hasRelatedWork W2038270131 @default.
- W2012037611 hasRelatedWork W2062451809 @default.
- W2012037611 hasRelatedWork W2149636727 @default.
- W2012037611 hasRelatedWork W2884761031 @default.
- W2012037611 hasVolume "22" @default.
- W2012037611 isParatext "false" @default.
- W2012037611 isRetracted "false" @default.
- W2012037611 magId "2012037611" @default.
- W2012037611 workType "article" @default.