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• W2012044797 abstract "Abstract Objective A non-degenerative etiology is supported by a normal SPI [normal SPECT with 123 I-Ioflupane (SPI)] in a patient with movement disorders (MD). Method A total of 196 SPIs were conducted during the period of 2004/05. Of these, 44 were selected in order to rule out degenerative MD (DMD), the results being normal in these patients. The clinical background of these patients were reviewed in a minimum period of 24 months (range 24-40), collecting the diagnoses reached by the neurology specialists. The SPIs were evaluated using a consensus, according to subjective criteria and quantification. Results Thirty-six of the 44 patients (81%) were identified at 2 years of having nondegenerative movement disorders: 18 as essential tremor, 5 as drug-induced disorder, 4 as vascular disease, 3 as peripheral polyneuropathy, 2 postural tremors, 1 writer's cramp, 1 psychogenic tremor, 1 intercranial hypertension and 1 fibromyalgia. The remaining 8 patients were diagnosed with Parkinson's disease in 5 cases, 1 corticobasal degeneration, 1 multisystemic atrophy and another degenerative Parkinsonism with unclear etiology. Conclusion The SPI in our hospital has a lower negative predictive value than the data reported in the literature. The false negatives could be explained because most of our patients come from neurologist physicians who are not movement disorder experts. In addition, a small proportion of degenerative Parkinsonism could evolve with normal SPI." @default.
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• W2012044797 date "2009-01-01" @default.
• W2012044797 modified "2023-09-24" @default.
• W2012044797 title "Negative Predictive Value of the SPECT with 123I Loflupane in movement disorders" @default.
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• W2012044797 doi "https://doi.org/10.1016/s1578-200x(09)70009-9" @default.
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