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- W20120498 abstract "The study of the spatial organization and dynamics of reentrant activity in three-dimensional (3D) cardiac muscle is crucial to the understanding of polymorphic ventricular tachycardia and fibrillation. Although the experimental knowledge about 3D reentry propagation in the heart remains very limited, because of the enormous technical difficulties of 3D mapping, there has been significant progress in theory and computer modeling of 3D reentry. This chapter reviews some of the major results of these studies, including the most recent developments not reflected in the previous editions of this book. 1 2 In particular, the role of myocardial structure, in the initiation, dynamics, and shaping of 3D reentry, which has been elucidated during past 3 years, is discussed. The emerging experimental approaches for imaging 3D reentry concealed inside the myocardial wall also is briefly described. As in the previous editions of this book, we have attempted to minimize technical detail to make the text accessible to a broad audience of basic and clinical cardiac electrophysiologists and at the same time to preserve the basic terminology accepted in the theoretical literature. Specifically, we continue using the terms scroll wave and filament for 3D reentry and its organizing center, respectively. We believe that becoming familiar with a more general terminology benefits those who would like to gain a deeper insight into the theoretical and vast experimental literature on “reentry-like” phenomena in biologic and chemical excitable systems. We also assume that the reader is familiar with the concept of spiral wave reentry. 3 4 (For review see Chapter 35 , Chapter 36 , and Chapter 37 .)" @default.
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- W20120498 date "2004-01-01" @default.
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- W20120498 title "Scroll Waves in Three Dimensions" @default.
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