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• W2012051738 abstract "Phase-contrast imaging methods exploit variations in an object&#x2019;s refractive index distribution to permit the visualization of subtle features that may have very similar optical absorption properties. Although phase-contrast is often viewed as being desirable in many biomedical applications, its relative influence on signal detectability when both absorption- and phase-contrast are present remains relatively unexplored. In this work, we investigate the ideal Bayesian observer signal-to-noise ratio in phase-contrast imaging for a signal-known-exactly/background-known exactly detection task involving a weak signal. We demonstrate that this signal detectability measure can be decomposed into three contributions that have distinct interpretations associated with the imaging physics." @default.
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• W2012051738 date "2010-11-23" @default.
• W2012051738 modified "2023-10-09" @default.
• W2012051738 title "Analysis of ideal observer signal detectability in phase-contrast imaging employing linear shift-invariant optical systems" @default.
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• W2012051738 doi "https://doi.org/10.1364/josaa.27.002648" @default.
• W2012051738 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2997532" @default.
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