FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012064870> ?p ?o ?g. }

• W2012064870 endingPage "e52058" @default.
• W2012064870 startingPage "e52058" @default.
• W2012064870 abstract "The purpose of this project was to evaluate the influence of circulating endothelial progenitor cells (EPCs) and platelet microparticles (PMPs) on blood platelet function in experimental hypertension associated with hypercholesterolemia.Golden Syrian hamsters were divided in six groups: (i) control, C; (ii) hypertensive-hypercholesterolemic, HH; (iii) 'prevention', HHin-EPCs, HH animals fed a HH diet and treated with EPCs; (iv) 'regression', HHfin-EPCs, HH treated with EPCs after HH feeding; (v) HH treated with PMPs, HH-PMPs, and (vi) HH treated with EPCs and PMPs, HH-EPCs-PMPs.Compared to HH group, the platelets from HHin-EPCs and HHfin-EPCs groups showed a reduction of: (i) activation, reflected by decreased integrin 3β, FAK, PI3K, src protein expression; (ii) secreted molecules as: SDF-1, MCP-1, RANTES, VEGF, PF4, PDGF and (iii) expression of pro-inflammatory molecules as: SDF-1, MCP-1, RANTES, IL-6, IL-1β; TFPI secretion was increased. Compared to HH group, platelets of HH-PMPs group showed increased activation, molecules release and proteins expression. Compared to HH-PMPs group the combination EPCs with PMPs treatment induced a decrease of all investigated platelet molecules, however not comparable with that recorded when EPC individual treatment was applied.EPCs have the ability to reduce platelet activation and to modulate their pro-inflammatory and anti-thrombogenic properties in hypertension associated with hypercholesterolemia. Although, PMPs have several beneficial effects in combination with EPCs, these did not improve the EPC effects. These findings reveal a new biological role of circulating EPCs in platelet function regulation, and may contribute to understand their cross talk, and the mechanisms of atherosclerosis." @default.
• W2012064870 created "2016-06-24" @default.
• W2012064870 creator A5046504961 @default.
• W2012064870 creator A5063014508 @default.
• W2012064870 creator A5066199761 @default.
• W2012064870 creator A5066387824 @default.
• W2012064870 creator A5075517960 @default.
• W2012064870 date "2013-01-25" @default.
• W2012064870 modified "2023-10-07" @default.
• W2012064870 title "Circulating Endothelial Progenitor Cell and Platelet Microparticle Impact on Platelet Activation in Hypertension Associated with Hypercholesterolemia" @default.
• W2012064870 cites W1522733054 @default.
• W2012064870 cites W1533864997 @default.
• W2012064870 cites W1973319320 @default.
• W2012064870 cites W1986991023 @default.
• W2012064870 cites W1989298176 @default.
• W2012064870 cites W1989741387 @default.
• W2012064870 cites W1991835908 @default.
• W2012064870 cites W1994953171 @default.
• W2012064870 cites W2000815276 @default.
• W2012064870 cites W2004653956 @default.
• W2012064870 cites W2010920888 @default.
• W2012064870 cites W2015086840 @default.
• W2012064870 cites W2015139547 @default.
• W2012064870 cites W2021685339 @default.
• W2012064870 cites W2021861291 @default.
• W2012064870 cites W2022628951 @default.
• W2012064870 cites W2026768387 @default.
• W2012064870 cites W2032811951 @default.
• W2012064870 cites W2033283451 @default.
• W2012064870 cites W2037960045 @default.
• W2012064870 cites W2047438335 @default.
• W2012064870 cites W2057617706 @default.
• W2012064870 cites W2057744541 @default.
• W2012064870 cites W2058217708 @default.
• W2012064870 cites W2060499390 @default.
• W2012064870 cites W2063175537 @default.
• W2012064870 cites W2071469535 @default.
• W2012064870 cites W2085350659 @default.
• W2012064870 cites W2087120448 @default.
• W2012064870 cites W2099450039 @default.
• W2012064870 cites W2109773324 @default.
• W2012064870 cites W2109880818 @default.
• W2012064870 cites W2121263655 @default.
• W2012064870 cites W2128283720 @default.
• W2012064870 cites W2129206637 @default.
• W2012064870 cites W2138264396 @default.
• W2012064870 cites W2140151140 @default.
• W2012064870 cites W2140229204 @default.
• W2012064870 cites W2145007557 @default.
• W2012064870 cites W2148993566 @default.
• W2012064870 cites W2155560850 @default.
• W2012064870 cites W2155857605 @default.
• W2012064870 cites W2156502101 @default.
• W2012064870 cites W2160359084 @default.
• W2012064870 cites W2163512781 @default.
• W2012064870 cites W2165510377 @default.
• W2012064870 cites W2169916808 @default.
• W2012064870 cites W2460470086 @default.
• W2012064870 cites W2615170291 @default.
• W2012064870 doi "https://doi.org/10.1371/journal.pone.0052058" @default.
• W2012064870 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3556069" @default.
• W2012064870 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23372649" @default.
• W2012064870 hasPublicationYear "2013" @default.
• W2012064870 type Work @default.
• W2012064870 sameAs 2012064870 @default.
• W2012064870 citedByCount "23" @default.
• W2012064870 countsByYear W20120648702013 @default.
• W2012064870 countsByYear W20120648702015 @default.
• W2012064870 countsByYear W20120648702016 @default.
• W2012064870 countsByYear W20120648702017 @default.
• W2012064870 countsByYear W20120648702018 @default.
• W2012064870 countsByYear W20120648702019 @default.
• W2012064870 countsByYear W20120648702020 @default.
• W2012064870 countsByYear W20120648702021 @default.
• W2012064870 crossrefType "journal-article" @default.
• W2012064870 hasAuthorship W2012064870A5046504961 @default.
• W2012064870 hasAuthorship W2012064870A5063014508 @default.
• W2012064870 hasAuthorship W2012064870A5066199761 @default.
• W2012064870 hasAuthorship W2012064870A5066387824 @default.
• W2012064870 hasAuthorship W2012064870A5075517960 @default.
• W2012064870 hasBestOaLocation W20120648701 @default.
• W2012064870 hasConcept C126322002 @default.
• W2012064870 hasConcept C134018914 @default.
• W2012064870 hasConcept C185592680 @default.
• W2012064870 hasConcept C201750760 @default.
• W2012064870 hasConcept C2780152582 @default.
• W2012064870 hasConcept C28328180 @default.
• W2012064870 hasConcept C3018697912 @default.
• W2012064870 hasConcept C71924100 @default.
• W2012064870 hasConcept C86803240 @default.
• W2012064870 hasConcept C89560881 @default.
• W2012064870 hasConcept C95444343 @default.
• W2012064870 hasConceptScore W2012064870C126322002 @default.
• W2012064870 hasConceptScore W2012064870C134018914 @default.
• W2012064870 hasConceptScore W2012064870C185592680 @default.
• W2012064870 hasConceptScore W2012064870C201750760 @default.
• W2012064870 hasConceptScore W2012064870C2780152582 @default.
• W2012064870 hasConceptScore W2012064870C28328180 @default.

• next