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- W2012068942 abstract "The ability of the rat diaphragm to produce inositol 1,4,5-trisphosphate (InsP3) in response to a maximal contractile stimulus was determine in vitro in both fatigued and nonfatigued diaphragms. InsP3 was produced during a maximal contraction of the diaphragm. After inducing fatigue, there was a significant reduction in the production of InsP3 compared with that in nonfatigued muscle. The maximal force generated by the diaphragm was also decreased after fatigue. A significant positive linear correlation was found between the force developed by the diaphragm and the amount of InsP3 liberated." @default.
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- W2012068942 date "1990-03-01" @default.
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- W2012068942 title "Diaphragmatic Fatigue Is Associated with Decreased Inositol 1,4,5-Trisphosphate Formation" @default.
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- W2012068942 doi "https://doi.org/10.1164/ajrccm/141.3.792" @default.
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