FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012074621> ?p ?o ?g. }

• W2012074621 endingPage "6133" @default.
• W2012074621 startingPage "6126" @default.
• W2012074621 abstract "ABSTRACT In Anabaena sp. strain PCC 7120, differentiation of heterocysts takes place in response to the external cue of combined nitrogen deprivation, allowing the organism to fix atmospheric nitrogen in oxic environments. NtcA, a global transcriptional regulator of cyanobacteria, is required for activation of the expression of multiple genes involved in heterocyst differentiation, including key regulators that are specific to the process. We have set up a fully defined in vitro system, which includes the purified Anabaena RNA polymerase, and have studied the effects of NtcA and its signaling effector 2-oxoglutarate on RNA polymerase binding, open complex formation, and transcript production from promoters of the hetC , nrrA , and devB genes that are activated by NtcA at different stages of heterocyst differentiation. Both RNA polymerase and NtcA could specifically bind to the target DNA in the absence of any effector. 2-Oxoglutarate had a moderate positive effect on NtcA binding, and NtcA had a limited positive effect on RNA polymerase recruitment at the promoters. However, a stringent requirement of both NtcA and 2-oxoglutarate was observed for the detection of open complexes and transcript production at the three investigated promoters. These results support a key role for 2-oxoglutarate in transcription activation in the developing heterocyst." @default.
• W2012074621 created "2016-06-24" @default.
• W2012074621 creator A5055766909 @default.
• W2012074621 creator A5059683644 @default.
• W2012074621 creator A5083259145 @default.
• W2012074621 date "2008-09-15" @default.
• W2012074621 modified "2023-09-30" @default.
• W2012074621 title "Transcription Activation by NtcA and 2-Oxoglutarate of Three Genes Involved in Heterocyst Differentiation in the Cyanobacterium <i>Anabaena</i> sp. Strain PCC 7120" @default.
• W2012074621 cites W1505843411 @default.
• W2012074621 cites W1587333710 @default.
• W2012074621 cites W1600883459 @default.
• W2012074621 cites W1671777287 @default.
• W2012074621 cites W1889215360 @default.
• W2012074621 cites W1967158241 @default.
• W2012074621 cites W1967250666 @default.
• W2012074621 cites W1968809164 @default.
• W2012074621 cites W1969873629 @default.
• W2012074621 cites W1972120140 @default.
• W2012074621 cites W1976749785 @default.
• W2012074621 cites W1981092872 @default.
• W2012074621 cites W1989075680 @default.
• W2012074621 cites W1998621506 @default.
• W2012074621 cites W2000283762 @default.
• W2012074621 cites W2001394772 @default.
• W2012074621 cites W2007397338 @default.
• W2012074621 cites W2025041465 @default.
• W2012074621 cites W2027643541 @default.
• W2012074621 cites W2036985332 @default.
• W2012074621 cites W2046366827 @default.
• W2012074621 cites W2051646663 @default.
• W2012074621 cites W2052341043 @default.
• W2012074621 cites W2066839663 @default.
• W2012074621 cites W2071421685 @default.
• W2012074621 cites W2083444458 @default.
• W2012074621 cites W2092236951 @default.
• W2012074621 cites W2102303488 @default.
• W2012074621 cites W2106894138 @default.
• W2012074621 cites W2111141573 @default.
• W2012074621 cites W2114767994 @default.
• W2012074621 cites W2120529104 @default.
• W2012074621 cites W2124220073 @default.
• W2012074621 cites W2125922194 @default.
• W2012074621 cites W2125993411 @default.
• W2012074621 cites W2133705635 @default.
• W2012074621 cites W2135054636 @default.
• W2012074621 cites W2144825804 @default.
• W2012074621 cites W2150902321 @default.
• W2012074621 cites W2151918395 @default.
• W2012074621 cites W2152776516 @default.
• W2012074621 cites W2161560166 @default.
• W2012074621 cites W2164320831 @default.
• W2012074621 cites W2177265400 @default.
• W2012074621 cites W4229692412 @default.
• W2012074621 cites W4293247451 @default.
• W2012074621 cites W4323966474 @default.
• W2012074621 doi "https://doi.org/10.1128/jb.00787-08" @default.
• W2012074621 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2546789" @default.
• W2012074621 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18658268" @default.
• W2012074621 hasPublicationYear "2008" @default.
• W2012074621 type Work @default.
• W2012074621 sameAs 2012074621 @default.
• W2012074621 citedByCount "58" @default.
• W2012074621 countsByYear W20120746212012 @default.
• W2012074621 countsByYear W20120746212013 @default.
• W2012074621 countsByYear W20120746212014 @default.
• W2012074621 countsByYear W20120746212015 @default.
• W2012074621 countsByYear W20120746212016 @default.
• W2012074621 countsByYear W20120746212017 @default.
• W2012074621 countsByYear W20120746212018 @default.
• W2012074621 countsByYear W20120746212019 @default.
• W2012074621 countsByYear W20120746212020 @default.
• W2012074621 countsByYear W20120746212021 @default.
• W2012074621 countsByYear W20120746212022 @default.
• W2012074621 crossrefType "journal-article" @default.
• W2012074621 hasAuthorship W2012074621A5055766909 @default.
• W2012074621 hasAuthorship W2012074621A5059683644 @default.
• W2012074621 hasAuthorship W2012074621A5083259145 @default.
• W2012074621 hasBestOaLocation W20120746211 @default.
• W2012074621 hasConcept C101762097 @default.
• W2012074621 hasConcept C104317684 @default.
• W2012074621 hasConcept C138885662 @default.
• W2012074621 hasConcept C150194340 @default.
• W2012074621 hasConcept C165864922 @default.
• W2012074621 hasConcept C179926584 @default.
• W2012074621 hasConcept C24417256 @default.
• W2012074621 hasConcept C2776449523 @default.
• W2012074621 hasConcept C2777530773 @default.
• W2012074621 hasConcept C2779669040 @default.
• W2012074621 hasConcept C41895202 @default.
• W2012074621 hasConcept C47319516 @default.
• W2012074621 hasConcept C51785407 @default.
• W2012074621 hasConcept C523546767 @default.
• W2012074621 hasConcept C54355233 @default.
• W2012074621 hasConcept C64350747 @default.
• W2012074621 hasConcept C67705224 @default.
• W2012074621 hasConcept C86339819 @default.
• W2012074621 hasConcept C86803240 @default.
• W2012074621 hasConcept C95444343 @default.

• next