Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012076125> ?p ?o ?g. }
- W2012076125 endingPage "578" @default.
- W2012076125 startingPage "569" @default.
- W2012076125 abstract "A pyrolysis-negative ion mass spectrometry (Pyr-NIMS) is used for the monitoring of enzymatic hydrolysis of penicillin G (Pen G) to 6-aminopenicillanic acid (6-APA) and phenyl acetic acid (PAA). The high sensitivity and rapid response time of Pyr-NIMS allow its application to the simultaneously determination of these compounds. The mass to charge (m/z) values of 262, 156 and 135 of Pen G, 6-APA and PAA respectively, are used for the quantitative measurements by selected ion monitoring (SIM). The limit of detection (LOD), linearity and relative standard deviation (n=5) are 10 ng ml−1, 100 ng ml−1–1000 mg ml−1 and 1.5%, respectively The results are compared with high performance liquid chromatography (HPLC). An important advantage of the presented analytical system is the high linearity of signals without preliminary separation and recalibration. The main and interactive effects of pH, temperature and concentration of Pen G for enzymatic hydrolysis of Pen G are studied. Optimize conditions of pH (8), temperature (28 °C) and concentration of Pen G (12% w/v) in real samples are obtained." @default.
- W2012076125 created "2016-06-24" @default.
- W2012076125 creator A5018804590 @default.
- W2012076125 creator A5023962970 @default.
- W2012076125 creator A5071478931 @default.
- W2012076125 creator A5085245756 @default.
- W2012076125 creator A5086842192 @default.
- W2012076125 date "2002-07-01" @default.
- W2012076125 modified "2023-09-25" @default.
- W2012076125 title "Monitoring of enzymatic hydrolysis of penicillin G by pyrolysis-negative ion mass spectrometry" @default.
- W2012076125 cites W1963508325 @default.
- W2012076125 cites W1965431799 @default.
- W2012076125 cites W1967964824 @default.
- W2012076125 cites W1991733426 @default.
- W2012076125 cites W1993470367 @default.
- W2012076125 cites W2012969837 @default.
- W2012076125 cites W2014502706 @default.
- W2012076125 cites W2021785993 @default.
- W2012076125 cites W2022196810 @default.
- W2012076125 cites W2022939484 @default.
- W2012076125 cites W2023980374 @default.
- W2012076125 cites W2029915782 @default.
- W2012076125 cites W2034850779 @default.
- W2012076125 cites W2036528005 @default.
- W2012076125 cites W2041005651 @default.
- W2012076125 cites W2042742579 @default.
- W2012076125 cites W2048571933 @default.
- W2012076125 cites W2049177637 @default.
- W2012076125 cites W2049178329 @default.
- W2012076125 cites W2052136626 @default.
- W2012076125 cites W2052454197 @default.
- W2012076125 cites W2052640888 @default.
- W2012076125 cites W2055075947 @default.
- W2012076125 cites W2057496759 @default.
- W2012076125 cites W2060758397 @default.
- W2012076125 cites W2063786947 @default.
- W2012076125 cites W2064359006 @default.
- W2012076125 cites W2068122446 @default.
- W2012076125 cites W2071351222 @default.
- W2012076125 cites W2088636298 @default.
- W2012076125 cites W2092652632 @default.
- W2012076125 cites W2107626906 @default.
- W2012076125 cites W2161175048 @default.
- W2012076125 cites W2614177741 @default.
- W2012076125 cites W4231769667 @default.
- W2012076125 doi "https://doi.org/10.1016/s0731-7085(02)00099-7" @default.
- W2012076125 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12062658" @default.
- W2012076125 hasPublicationYear "2002" @default.
- W2012076125 type Work @default.
- W2012076125 sameAs 2012076125 @default.
- W2012076125 citedByCount "8" @default.
- W2012076125 crossrefType "journal-article" @default.
- W2012076125 hasAuthorship W2012076125A5018804590 @default.
- W2012076125 hasAuthorship W2012076125A5023962970 @default.
- W2012076125 hasAuthorship W2012076125A5071478931 @default.
- W2012076125 hasAuthorship W2012076125A5085245756 @default.
- W2012076125 hasAuthorship W2012076125A5086842192 @default.
- W2012076125 hasConcept C113196181 @default.
- W2012076125 hasConcept C119128265 @default.
- W2012076125 hasConcept C162356407 @default.
- W2012076125 hasConcept C178790620 @default.
- W2012076125 hasConcept C179302884 @default.
- W2012076125 hasConcept C179998833 @default.
- W2012076125 hasConcept C181199279 @default.
- W2012076125 hasConcept C185592680 @default.
- W2012076125 hasConcept C205345274 @default.
- W2012076125 hasConcept C2776673659 @default.
- W2012076125 hasConcept C2777451570 @default.
- W2012076125 hasConcept C33633552 @default.
- W2012076125 hasConcept C43617362 @default.
- W2012076125 hasConcept C53270655 @default.
- W2012076125 hasConcept C94412978 @default.
- W2012076125 hasConceptScore W2012076125C113196181 @default.
- W2012076125 hasConceptScore W2012076125C119128265 @default.
- W2012076125 hasConceptScore W2012076125C162356407 @default.
- W2012076125 hasConceptScore W2012076125C178790620 @default.
- W2012076125 hasConceptScore W2012076125C179302884 @default.
- W2012076125 hasConceptScore W2012076125C179998833 @default.
- W2012076125 hasConceptScore W2012076125C181199279 @default.
- W2012076125 hasConceptScore W2012076125C185592680 @default.
- W2012076125 hasConceptScore W2012076125C205345274 @default.
- W2012076125 hasConceptScore W2012076125C2776673659 @default.
- W2012076125 hasConceptScore W2012076125C2777451570 @default.
- W2012076125 hasConceptScore W2012076125C33633552 @default.
- W2012076125 hasConceptScore W2012076125C43617362 @default.
- W2012076125 hasConceptScore W2012076125C53270655 @default.
- W2012076125 hasConceptScore W2012076125C94412978 @default.
- W2012076125 hasIssue "3" @default.
- W2012076125 hasLocation W20120761251 @default.
- W2012076125 hasLocation W20120761252 @default.
- W2012076125 hasOpenAccess W2012076125 @default.
- W2012076125 hasPrimaryLocation W20120761251 @default.
- W2012076125 hasRelatedWork W1603333022 @default.
- W2012076125 hasRelatedWork W1964259887 @default.
- W2012076125 hasRelatedWork W1998279148 @default.
- W2012076125 hasRelatedWork W2013299392 @default.
- W2012076125 hasRelatedWork W2032191029 @default.
- W2012076125 hasRelatedWork W2044206509 @default.