FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012076369> ?p ?o ?g. }

• W2012076369 endingPage "4" @default.
• W2012076369 startingPage "1" @default.
• W2012076369 abstract "Frontal sections including temporal isocortex, entorhinal region and hippocampus from aged domestic animals (dog, cat, horse, sheep and goat) were studied for Alzheimer-related changes using immunostaining with the AT8 antibody for abnormally phosphorylated tau protein and selective silver techniques for A4 amyloid and neurofibrillary changes of the Alzheimer type. The material available to us did not show A4 amyloid deposits or argyrophilic neurofibrillary changes. Only the brains of aged sheep and goat exhibited the presence of AT8-immunoreactive pyramidal cells in the entorhinal region and hippocampal formation. Two groups of AT8-positive neurons could be observed: The first group contained evenly distributed immunoreactive material in all parts of the soma, the dendrites and the axon. The neuronal processes appeared quite normal. The second group, however, showed conspicuous changes in the cellular processes consisting of a loss of immunoreactivity within the axon and the proximal dendrites and the appearance of intensely stained swellings within the curved distal dendrites. These changes were closely reminiscent to alterations of the cytoskeleton known to occur at the same location in the aging human brain and in Alzheimer's disease. The findings justify a closer look at sheep and goat when searching for suitable animal models for experimental studies of the conditions responsible for the development of Alzheimer-related neurofibrillary changes." @default.
• W2012076369 created "2016-06-24" @default.
• W2012076369 creator A5016965073 @default.
• W2012076369 creator A5024213283 @default.
• W2012076369 creator A5085570825 @default.
• W2012076369 date "1994-04-01" @default.
• W2012076369 modified "2023-09-27" @default.
• W2012076369 title "Abnormally phosphorylated tau protein related to the formation of neurofibrillary tangles and neuropil threads in the cerebral cortex of sheep and goat" @default.
• W2012076369 cites W1971541898 @default.
• W2012076369 cites W1982377472 @default.
• W2012076369 cites W1984827962 @default.
• W2012076369 cites W1987493138 @default.
• W2012076369 cites W1993940897 @default.
• W2012076369 cites W1998319561 @default.
• W2012076369 cites W2004347786 @default.
• W2012076369 cites W2015563160 @default.
• W2012076369 cites W2015860144 @default.
• W2012076369 cites W2024949566 @default.
• W2012076369 cites W2032009532 @default.
• W2012076369 cites W2036642860 @default.
• W2012076369 cites W2039468514 @default.
• W2012076369 cites W2045658045 @default.
• W2012076369 cites W2052742260 @default.
• W2012076369 cites W2064751532 @default.
• W2012076369 cites W2064762646 @default.
• W2012076369 cites W2076384868 @default.
• W2012076369 cites W2077422298 @default.
• W2012076369 cites W2086552679 @default.
• W2012076369 cites W2091659793 @default.
• W2012076369 cites W2118012105 @default.
• W2012076369 cites W2131478918 @default.
• W2012076369 cites W2147146769 @default.
• W2012076369 cites W2327309645 @default.
• W2012076369 doi "https://doi.org/10.1016/0304-3940(94)90589-4" @default.
• W2012076369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7521944" @default.
• W2012076369 hasPublicationYear "1994" @default.
• W2012076369 type Work @default.
• W2012076369 sameAs 2012076369 @default.
• W2012076369 citedByCount "124" @default.
• W2012076369 countsByYear W20120763692012 @default.
• W2012076369 countsByYear W20120763692013 @default.
• W2012076369 countsByYear W20120763692014 @default.
• W2012076369 countsByYear W20120763692015 @default.
• W2012076369 countsByYear W20120763692016 @default.
• W2012076369 countsByYear W20120763692017 @default.
• W2012076369 countsByYear W20120763692018 @default.
• W2012076369 countsByYear W20120763692019 @default.
• W2012076369 countsByYear W20120763692020 @default.
• W2012076369 countsByYear W20120763692021 @default.
• W2012076369 countsByYear W20120763692022 @default.
• W2012076369 crossrefType "journal-article" @default.
• W2012076369 hasAuthorship W2012076369A5016965073 @default.
• W2012076369 hasAuthorship W2012076369A5024213283 @default.
• W2012076369 hasAuthorship W2012076369A5085570825 @default.
• W2012076369 hasConcept C105702510 @default.
• W2012076369 hasConcept C142724271 @default.
• W2012076369 hasConcept C148762608 @default.
• W2012076369 hasConcept C157207234 @default.
• W2012076369 hasConcept C169760540 @default.
• W2012076369 hasConcept C204232928 @default.
• W2012076369 hasConcept C2777633098 @default.
• W2012076369 hasConcept C2777831001 @default.
• W2012076369 hasConcept C2778670691 @default.
• W2012076369 hasConcept C2779134260 @default.
• W2012076369 hasConcept C2779530196 @default.
• W2012076369 hasConcept C2779721402 @default.
• W2012076369 hasConcept C2780715579 @default.
• W2012076369 hasConcept C2781041448 @default.
• W2012076369 hasConcept C2781161787 @default.
• W2012076369 hasConcept C4224716 @default.
• W2012076369 hasConcept C502032728 @default.
• W2012076369 hasConcept C529278444 @default.
• W2012076369 hasConcept C68026918 @default.
• W2012076369 hasConcept C71924100 @default.
• W2012076369 hasConcept C86803240 @default.
• W2012076369 hasConceptScore W2012076369C105702510 @default.
• W2012076369 hasConceptScore W2012076369C142724271 @default.
• W2012076369 hasConceptScore W2012076369C148762608 @default.
• W2012076369 hasConceptScore W2012076369C157207234 @default.
• W2012076369 hasConceptScore W2012076369C169760540 @default.
• W2012076369 hasConceptScore W2012076369C204232928 @default.
• W2012076369 hasConceptScore W2012076369C2777633098 @default.
• W2012076369 hasConceptScore W2012076369C2777831001 @default.
• W2012076369 hasConceptScore W2012076369C2778670691 @default.
• W2012076369 hasConceptScore W2012076369C2779134260 @default.
• W2012076369 hasConceptScore W2012076369C2779530196 @default.
• W2012076369 hasConceptScore W2012076369C2779721402 @default.
• W2012076369 hasConceptScore W2012076369C2780715579 @default.
• W2012076369 hasConceptScore W2012076369C2781041448 @default.
• W2012076369 hasConceptScore W2012076369C2781161787 @default.
• W2012076369 hasConceptScore W2012076369C4224716 @default.
• W2012076369 hasConceptScore W2012076369C502032728 @default.
• W2012076369 hasConceptScore W2012076369C529278444 @default.
• W2012076369 hasConceptScore W2012076369C68026918 @default.
• W2012076369 hasConceptScore W2012076369C71924100 @default.
• W2012076369 hasConceptScore W2012076369C86803240 @default.
• W2012076369 hasIssue "1-2" @default.
• W2012076369 hasLocation W20120763691 @default.

• next