Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012077435> ?p ?o ?g. }
- W2012077435 endingPage "140" @default.
- W2012077435 startingPage "134" @default.
- W2012077435 abstract "The ability of hallucinogens to increase extracellular glutamate in the prefrontal cortex (PFC) was assessed by in vivo microdialysis. The hallucinogen lysergic acid diethylamide (LSD; 0.1 mg/kg, i.p.) caused a time-dependent increase in PFC glutamate that was blocked by the 5-HT(2A) antagonist M100907 (0.05 mg/kg, i.p.). Similarly, the 5-HT(2A/C) agonist [-]-2,5-dimethoxy-4-methylamphetamine (DOM; 0.6 mg/kg, i.p.), which is a phenethylamine hallucinogen, increased glutamate to 206% above saline-treated controls. When LSD (10 microM) was directly applied to the PFC by reverse dialysis, a rapid increase in PFC glutamate levels was observed. Glutamate levels in the PFC remained elevated after the drug infusion was discontinued. These data provide direct evidence in vivo for the hypothesis that an enhanced release of glutamate is a common mechanism in the action of hallucinogens." @default.
- W2012077435 created "2016-06-24" @default.
- W2012077435 creator A5003200265 @default.
- W2012077435 creator A5010350536 @default.
- W2012077435 creator A5053320571 @default.
- W2012077435 creator A5065486287 @default.
- W2012077435 creator A5083790675 @default.
- W2012077435 date "2004-10-01" @default.
- W2012077435 modified "2023-10-13" @default.
- W2012077435 title "Lysergic acid diethylamide and [−]-2,5-dimethoxy-4-methylamphetamine increase extracellular glutamate in rat prefrontal cortex" @default.
- W2012077435 cites W1518033152 @default.
- W2012077435 cites W1553790444 @default.
- W2012077435 cites W1914381346 @default.
- W2012077435 cites W192882819 @default.
- W2012077435 cites W1967653523 @default.
- W2012077435 cites W1977783792 @default.
- W2012077435 cites W1981875451 @default.
- W2012077435 cites W1993099609 @default.
- W2012077435 cites W1997058647 @default.
- W2012077435 cites W2004172377 @default.
- W2012077435 cites W2004656027 @default.
- W2012077435 cites W2004763052 @default.
- W2012077435 cites W2009823135 @default.
- W2012077435 cites W2010441130 @default.
- W2012077435 cites W2015011531 @default.
- W2012077435 cites W2019428032 @default.
- W2012077435 cites W2022909733 @default.
- W2012077435 cites W2025534288 @default.
- W2012077435 cites W2029267570 @default.
- W2012077435 cites W2031544765 @default.
- W2012077435 cites W2034005051 @default.
- W2012077435 cites W2034951640 @default.
- W2012077435 cites W2038393570 @default.
- W2012077435 cites W2038933762 @default.
- W2012077435 cites W2044239788 @default.
- W2012077435 cites W2044730840 @default.
- W2012077435 cites W2044745774 @default.
- W2012077435 cites W2050452462 @default.
- W2012077435 cites W2050865511 @default.
- W2012077435 cites W2053802427 @default.
- W2012077435 cites W2061506085 @default.
- W2012077435 cites W2067384745 @default.
- W2012077435 cites W2070477957 @default.
- W2012077435 cites W2072159859 @default.
- W2012077435 cites W2074483296 @default.
- W2012077435 cites W2076920165 @default.
- W2012077435 cites W2079106221 @default.
- W2012077435 cites W2082531935 @default.
- W2012077435 cites W2084757940 @default.
- W2012077435 cites W2085598752 @default.
- W2012077435 cites W2092204227 @default.
- W2012077435 cites W2099635835 @default.
- W2012077435 cites W2103903531 @default.
- W2012077435 cites W2106042714 @default.
- W2012077435 cites W2107985334 @default.
- W2012077435 cites W2111990860 @default.
- W2012077435 cites W2123354702 @default.
- W2012077435 cites W2138930549 @default.
- W2012077435 cites W2157025685 @default.
- W2012077435 cites W2163830705 @default.
- W2012077435 cites W2409471825 @default.
- W2012077435 cites W4245707768 @default.
- W2012077435 doi "https://doi.org/10.1016/j.brainres.2004.07.044" @default.
- W2012077435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15364028" @default.
- W2012077435 hasPublicationYear "2004" @default.
- W2012077435 type Work @default.
- W2012077435 sameAs 2012077435 @default.
- W2012077435 citedByCount "86" @default.
- W2012077435 countsByYear W20120774352012 @default.
- W2012077435 countsByYear W20120774352013 @default.
- W2012077435 countsByYear W20120774352014 @default.
- W2012077435 countsByYear W20120774352015 @default.
- W2012077435 countsByYear W20120774352016 @default.
- W2012077435 countsByYear W20120774352017 @default.
- W2012077435 countsByYear W20120774352018 @default.
- W2012077435 countsByYear W20120774352019 @default.
- W2012077435 countsByYear W20120774352020 @default.
- W2012077435 countsByYear W20120774352021 @default.
- W2012077435 countsByYear W20120774352022 @default.
- W2012077435 countsByYear W20120774352023 @default.
- W2012077435 crossrefType "journal-article" @default.
- W2012077435 hasAuthorship W2012077435A5003200265 @default.
- W2012077435 hasAuthorship W2012077435A5010350536 @default.
- W2012077435 hasAuthorship W2012077435A5053320571 @default.
- W2012077435 hasAuthorship W2012077435A5065486287 @default.
- W2012077435 hasAuthorship W2012077435A5083790675 @default.
- W2012077435 hasConcept C124315065 @default.
- W2012077435 hasConcept C150903083 @default.
- W2012077435 hasConcept C15744967 @default.
- W2012077435 hasConcept C169760540 @default.
- W2012077435 hasConcept C169900460 @default.
- W2012077435 hasConcept C170493617 @default.
- W2012077435 hasConcept C185592680 @default.
- W2012077435 hasConcept C207001950 @default.
- W2012077435 hasConcept C2775864247 @default.
- W2012077435 hasConcept C2776885963 @default.
- W2012077435 hasConcept C2778938600 @default.
- W2012077435 hasConcept C2779871769 @default.