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• W2012080968 abstract "The POMC gene is perhaps the most extensively studied member of the opioid/orphanin gene family. In Phylum Chordata this gene has been characterized in representatives of every class within the Gnathostomata, as well as in one representative agnathan vertebrate, the marine lamprey. This review provides a systematic overview of trends in the evolution of the melanocortins (ACTH/alpha-MSH, beta-MSH, gamma-MSH, and delta-MSH) and beta-endorphin in gnathostomes, and advances the hypothesis that the appearance of gamma-MSH occurred early in the radiation of the gnathostomes. A summary of the extensive work on POMC genes in the marine lamprey is also provided, as well as a reevaluation of the conserved regions in the sequence of CLIP (corticotropin-like-intermediate lobe peptide) in the POMC sequences of the various groups of gnathostomes." @default.
• W2012080968 created "2016-06-24" @default.
• W2012080968 creator A5037152382 @default.
• W2012080968 creator A5067636916 @default.
• W2012080968 date "2005-05-01" @default.
• W2012080968 modified "2023-09-26" @default.
• W2012080968 title "Trends in the evolution of the proopiomelanocortin gene" @default.
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• W2012080968 doi "https://doi.org/10.1016/j.ygcen.2005.02.003" @default.
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