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• W2012083151 abstract "An ultra-sensitive colorimetric method to quantitate hundreds of polynucleotide molecules by gold nanoparticles with silver enhancement has been developed. The hybridization products from the target polynucleotides with biotin-labeled probes and gold nanoparticle-functioned oligonucleotides were immobilized to microplates via avidin-biotin system, and the absorbance signals of gold nanoparticles were amplified by silver enhance solution. This sandwich colorimetric assay can detect as few as 600 molecules for single-strand oligonucleotides and as few as 6000 molecules for double-strand polynucleotides in a 50 microL reaction system." @default.
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• W2012083151 date "2006-10-01" @default.
• W2012083151 modified "2023-09-23" @default.
• W2012083151 title "Ultra-sensitive Colorimetric Method to Quantitate Hundreds of Polynucleotide Molecules by Gold Nanoparticles with Silver Enhancement" @default.
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• W2012083151 doi "https://doi.org/10.2116/analsci.22.1367" @default.
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