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- W2012085094 abstract "Stearic acid solid lipid nanoparticles (SLN) were prepared according to the coacervation technique, consisting in fatty acid precipitation of alkaline salt from a solution. SLN can encapsulate Amphotericin B with high efficiency in its monomeric form. SLN markedly increase in vitro drug toxicity towards Saccharomyces cerevisiae (taken as model yeast), expressed as potassium leakage. Yeast susceptibility towards Amphotericin B is increased when the drug is loaded in nanoparticles compared to the free drug, even if inhibition is limited by drug encapsulation within lipid matrix." @default.
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- W2012085094 date "2010-01-01" @default.
- W2012085094 modified "2023-10-14" @default.
- W2012085094 title "Amphotericin B loaded SLN prepared with the coacervation technique" @default.
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- W2012085094 doi "https://doi.org/10.1016/s1773-2247(10)50028-5" @default.
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