FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012091207> ?p ?o ?g. }

• W2012091207 endingPage "23" @default.
• W2012091207 startingPage "15" @default.
• W2012091207 abstract "• The N -methyltaurine conjugates of cholic and deoxycholic acids were identified in angelfish. • The authentic samples were synthesized from respective bile acids. • The structures of the novel conjugates were established by MS and NMR. • The conjugate of deoxycholic acid may have evolved to insure high bile acid concentrations. • The results suggest that angelfish possess an unusual intestinal microbiome. Two novel N -acyl amidated bile acids, N -methyltaurine conjugated cholic acid and N -methyltaurine conjugated deoxycholic acid, were found to be major biliary bile acids in two species of angelfish the regal ( Pygoplites diacanthus ) and the blue-girdled ( Pomacanthus navarchus ) angelfish. The identification was based on their having MS and NMR spectra identical to those of synthetic standards. A survey of biliary bile acids of 10 additional species of angelfish found 7 with N -methyltaurine conjugation. In all 12 species, conjugated deoxycholic acid (known to be formed by bacterial 7-dehydroxylation of cholic acid) was a major bile acid. In all previous studies of biliary bile acids in fish, deoxycholic acid has been present in only trace proportions. In addition, bile acid conjugation with N -methyltaurine has not been detected previously in any known vertebrate. N -methyltaurine conjugated bile acids are resistant to bacterial deconjugation and dehydroxylation, and such resistance to bacterial enzymes should aid in the maintenance of high concentrations of bile acids during lipid digestion. Our findings suggest that these species of angelfish have a novel microbiome in their intestine containing anaerobic bacteria, and describe the presence of N -methyltaurine conjugated bile acids that are resistant to bacterial attack." @default.
• W2012091207 created "2016-06-24" @default.
• W2012091207 creator A5023747207 @default.
• W2012091207 creator A5032445401 @default.
• W2012091207 creator A5033903854 @default.
• W2012091207 creator A5036816700 @default.
• W2012091207 creator A5045892040 @default.
• W2012091207 creator A5076930309 @default.
• W2012091207 creator A5081133688 @default.
• W2012091207 creator A5081941040 @default.
• W2012091207 creator A5084115145 @default.
• W2012091207 creator A5090844389 @default.
• W2012091207 date "2014-02-01" @default.
• W2012091207 modified "2023-10-16" @default.
• W2012091207 title "N-Methyltaurine N-acyl amidated bile acids and deoxycholic acid in the bile of angelfish (Pomacanthidae): A novel bile acid profile in Perciform fish" @default.
• W2012091207 cites W1483863421 @default.
• W2012091207 cites W1502644188 @default.
• W2012091207 cites W1602209617 @default.
• W2012091207 cites W1989839016 @default.
• W2012091207 cites W1992118967 @default.
• W2012091207 cites W1995640905 @default.
• W2012091207 cites W2003417360 @default.
• W2012091207 cites W2007994504 @default.
• W2012091207 cites W2020652894 @default.
• W2012091207 cites W2022460874 @default.
• W2012091207 cites W2051570780 @default.
• W2012091207 cites W2070278261 @default.
• W2012091207 cites W2071273298 @default.
• W2012091207 cites W2076452226 @default.
• W2012091207 cites W2131025132 @default.
• W2012091207 cites W2152438501 @default.
• W2012091207 cites W2164939422 @default.
• W2012091207 cites W2173893080 @default.
• W2012091207 cites W2345907270 @default.
• W2012091207 cites W2415958276 @default.
• W2012091207 doi "https://doi.org/10.1016/j.steroids.2013.11.014" @default.
• W2012091207 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24291417" @default.
• W2012091207 hasPublicationYear "2014" @default.
• W2012091207 type Work @default.
• W2012091207 sameAs 2012091207 @default.
• W2012091207 citedByCount "6" @default.
• W2012091207 countsByYear W20120912072014 @default.
• W2012091207 countsByYear W20120912072016 @default.
• W2012091207 countsByYear W20120912072018 @default.
• W2012091207 countsByYear W20120912072019 @default.
• W2012091207 countsByYear W20120912072020 @default.
• W2012091207 countsByYear W20120912072021 @default.
• W2012091207 crossrefType "journal-article" @default.
• W2012091207 hasAuthorship W2012091207A5023747207 @default.
• W2012091207 hasAuthorship W2012091207A5032445401 @default.
• W2012091207 hasAuthorship W2012091207A5033903854 @default.
• W2012091207 hasAuthorship W2012091207A5036816700 @default.
• W2012091207 hasAuthorship W2012091207A5045892040 @default.
• W2012091207 hasAuthorship W2012091207A5076930309 @default.
• W2012091207 hasAuthorship W2012091207A5081133688 @default.
• W2012091207 hasAuthorship W2012091207A5081941040 @default.
• W2012091207 hasAuthorship W2012091207A5084115145 @default.
• W2012091207 hasAuthorship W2012091207A5090844389 @default.
• W2012091207 hasConcept C185592680 @default.
• W2012091207 hasConcept C2775900799 @default.
• W2012091207 hasConcept C2779399885 @default.
• W2012091207 hasConcept C2780749602 @default.
• W2012091207 hasConcept C515207424 @default.
• W2012091207 hasConcept C55493867 @default.
• W2012091207 hasConcept C86803240 @default.
• W2012091207 hasConceptScore W2012091207C185592680 @default.
• W2012091207 hasConceptScore W2012091207C2775900799 @default.
• W2012091207 hasConceptScore W2012091207C2779399885 @default.
• W2012091207 hasConceptScore W2012091207C2780749602 @default.
• W2012091207 hasConceptScore W2012091207C515207424 @default.
• W2012091207 hasConceptScore W2012091207C55493867 @default.
• W2012091207 hasConceptScore W2012091207C86803240 @default.
• W2012091207 hasLocation W20120912071 @default.
• W2012091207 hasLocation W20120912072 @default.
• W2012091207 hasOpenAccess W2012091207 @default.
• W2012091207 hasPrimaryLocation W20120912071 @default.
• W2012091207 hasRelatedWork W1861979568 @default.
• W2012091207 hasRelatedWork W1904411989 @default.
• W2012091207 hasRelatedWork W1983517124 @default.
• W2012091207 hasRelatedWork W2012576067 @default.
• W2012091207 hasRelatedWork W2084807134 @default.
• W2012091207 hasRelatedWork W2089923064 @default.
• W2012091207 hasRelatedWork W2113892157 @default.
• W2012091207 hasRelatedWork W2791899145 @default.
• W2012091207 hasRelatedWork W2793293174 @default.
• W2012091207 hasRelatedWork W2948302576 @default.
• W2012091207 hasVolume "80" @default.
• W2012091207 isParatext "false" @default.
• W2012091207 isRetracted "false" @default.
• W2012091207 magId "2012091207" @default.
• W2012091207 workType "article" @default.