Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012091610> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2012091610 endingPage "3074" @default.
- W2012091610 startingPage "3071" @default.
- W2012091610 abstract "Transmural stimulation of the isolated adrenal gland of the rat and guinea pig results in secretion of catecholamine. The secretion is due to activation of cholinergic receptors of the adrenal medulla by acetylcholine released from splanchnic nerve terminals after transmural stimulation. Our aim was to see whether the same experimental technique could be used to directly excite the adrenal medullary cell membrane by electrical stimulation and whether such stimulation would result in secretion of catecholamines. We demonstrate here that a single electrical shock to the perfused adrenal gland of the rat results in massive secretion of epinephrine and norepinephrine. The secretion is directly related to the strength and duration of the applied stimulus over a wide range. Catecholamine secretion is unaffected by tetrodotoxin or hexamethonium/atropine but is abolished by Ca2+ lack or 3 mM Mn2+. We suggest that the adrenal medullary membrane undergoes nonpropagated electrotonic depolarization on electric stimulation and thereby voltage-dependent Ca2+ channels are opened to initiate secretion." @default.
- W2012091610 created "2016-06-24" @default.
- W2012091610 creator A5042264523 @default.
- W2012091610 creator A5078080372 @default.
- W2012091610 date "1982-05-01" @default.
- W2012091610 modified "2023-10-18" @default.
- W2012091610 title "Secretion of catecholamines from adrenal gland by a single electrical shock: electronic depolarization of medullary cell membrane." @default.
- W2012091610 cites W1992434989 @default.
- W2012091610 cites W1995837298 @default.
- W2012091610 cites W1998031030 @default.
- W2012091610 cites W2002093874 @default.
- W2012091610 cites W2019470602 @default.
- W2012091610 cites W2047721620 @default.
- W2012091610 cites W2049228395 @default.
- W2012091610 cites W2062986670 @default.
- W2012091610 cites W2069079626 @default.
- W2012091610 cites W2089463776 @default.
- W2012091610 doi "https://doi.org/10.1073/pnas.79.9.3071" @default.
- W2012091610 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/346351" @default.
- W2012091610 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6953450" @default.
- W2012091610 hasPublicationYear "1982" @default.
- W2012091610 type Work @default.
- W2012091610 sameAs 2012091610 @default.
- W2012091610 citedByCount "11" @default.
- W2012091610 countsByYear W20120916102016 @default.
- W2012091610 countsByYear W20120916102018 @default.
- W2012091610 countsByYear W20120916102021 @default.
- W2012091610 countsByYear W20120916102022 @default.
- W2012091610 crossrefType "journal-article" @default.
- W2012091610 hasAuthorship W2012091610A5042264523 @default.
- W2012091610 hasAuthorship W2012091610A5078080372 @default.
- W2012091610 hasBestOaLocation W20120916102 @default.
- W2012091610 hasConcept C126322002 @default.
- W2012091610 hasConcept C134018914 @default.
- W2012091610 hasConcept C185592680 @default.
- W2012091610 hasConcept C22885893 @default.
- W2012091610 hasConcept C24998067 @default.
- W2012091610 hasConcept C2775859304 @default.
- W2012091610 hasConcept C2775893369 @default.
- W2012091610 hasConcept C2775894120 @default.
- W2012091610 hasConcept C2776741303 @default.
- W2012091610 hasConcept C2777597313 @default.
- W2012091610 hasConcept C2780253649 @default.
- W2012091610 hasConcept C2780661788 @default.
- W2012091610 hasConcept C2780694816 @default.
- W2012091610 hasConcept C2780910648 @default.
- W2012091610 hasConcept C4141045 @default.
- W2012091610 hasConcept C49039625 @default.
- W2012091610 hasConcept C71924100 @default.
- W2012091610 hasConcept C86803240 @default.
- W2012091610 hasConceptScore W2012091610C126322002 @default.
- W2012091610 hasConceptScore W2012091610C134018914 @default.
- W2012091610 hasConceptScore W2012091610C185592680 @default.
- W2012091610 hasConceptScore W2012091610C22885893 @default.
- W2012091610 hasConceptScore W2012091610C24998067 @default.
- W2012091610 hasConceptScore W2012091610C2775859304 @default.
- W2012091610 hasConceptScore W2012091610C2775893369 @default.
- W2012091610 hasConceptScore W2012091610C2775894120 @default.
- W2012091610 hasConceptScore W2012091610C2776741303 @default.
- W2012091610 hasConceptScore W2012091610C2777597313 @default.
- W2012091610 hasConceptScore W2012091610C2780253649 @default.
- W2012091610 hasConceptScore W2012091610C2780661788 @default.
- W2012091610 hasConceptScore W2012091610C2780694816 @default.
- W2012091610 hasConceptScore W2012091610C2780910648 @default.
- W2012091610 hasConceptScore W2012091610C4141045 @default.
- W2012091610 hasConceptScore W2012091610C49039625 @default.
- W2012091610 hasConceptScore W2012091610C71924100 @default.
- W2012091610 hasConceptScore W2012091610C86803240 @default.
- W2012091610 hasIssue "9" @default.
- W2012091610 hasLocation W20120916101 @default.
- W2012091610 hasLocation W20120916102 @default.
- W2012091610 hasLocation W20120916103 @default.
- W2012091610 hasLocation W20120916104 @default.
- W2012091610 hasOpenAccess W2012091610 @default.
- W2012091610 hasPrimaryLocation W20120916101 @default.
- W2012091610 hasRelatedWork W2004734051 @default.
- W2012091610 hasRelatedWork W2012091610 @default.
- W2012091610 hasRelatedWork W2013389272 @default.
- W2012091610 hasRelatedWork W2014896485 @default.
- W2012091610 hasRelatedWork W2074299236 @default.
- W2012091610 hasRelatedWork W2335088811 @default.
- W2012091610 hasRelatedWork W2512605113 @default.
- W2012091610 hasRelatedWork W2758158127 @default.
- W2012091610 hasRelatedWork W2914911904 @default.
- W2012091610 hasRelatedWork W3136118295 @default.
- W2012091610 hasVolume "79" @default.
- W2012091610 isParatext "false" @default.
- W2012091610 isRetracted "false" @default.
- W2012091610 magId "2012091610" @default.
- W2012091610 workType "article" @default.