Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012097586> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2012097586 endingPage "1282" @default.
- W2012097586 startingPage "1275" @default.
- W2012097586 abstract "Human pre-B acute lymphocytic leukemia (ALL) cell line 697 contains a disease-specific chromosomal translocation, t(1;19), near the insulin receptor locus (INSR). Insulin binding, insulin receptor kinase and cell surface immunofluorescence experiments all show that 697 cells express more surface insulin receptors than 207 cells, a line of pre-B ALL cells that lack the t(1;19). Northern blot analysis confirms that 697 cells have increased levels of mRNA for the insulin receptor. Gene dosage and in situ hybridization analysis indicate that only two copies of the INSR locus are present in 697 cells, one on the translocation chromosome and one on the normal chromosome 19. The results described here demonstrate that transcriptional up-regulation of the INSR locus is correlated with the t(1;19) translocation found in human pre-B ALL cell line 697." @default.
- W2012097586 created "2016-06-24" @default.
- W2012097586 creator A5004654808 @default.
- W2012097586 creator A5022360724 @default.
- W2012097586 creator A5036382303 @default.
- W2012097586 creator A5073116324 @default.
- W2012097586 creator A5073519148 @default.
- W2012097586 date "1989-03-01" @default.
- W2012097586 modified "2023-09-25" @default.
- W2012097586 title "Insulin receptor overexpression in a human pre-B acute lymphocytic leukemia cell line with a t(1;19) chromosome translocation near the INSR locus" @default.
- W2012097586 cites W1484310192 @default.
- W2012097586 cites W1501457235 @default.
- W2012097586 cites W1503502817 @default.
- W2012097586 cites W1553542610 @default.
- W2012097586 cites W1963639319 @default.
- W2012097586 cites W1965263613 @default.
- W2012097586 cites W1966369545 @default.
- W2012097586 cites W1990516512 @default.
- W2012097586 cites W1991710558 @default.
- W2012097586 cites W2011836510 @default.
- W2012097586 cites W2014497818 @default.
- W2012097586 cites W2014669590 @default.
- W2012097586 cites W2029987769 @default.
- W2012097586 cites W2037510115 @default.
- W2012097586 cites W2057375535 @default.
- W2012097586 cites W2060333964 @default.
- W2012097586 cites W2070197254 @default.
- W2012097586 cites W2091916041 @default.
- W2012097586 cites W2100837269 @default.
- W2012097586 cites W2122567567 @default.
- W2012097586 cites W2314458949 @default.
- W2012097586 cites W4233432336 @default.
- W2012097586 cites W89089254 @default.
- W2012097586 doi "https://doi.org/10.1016/0006-291x(89)92248-1" @default.
- W2012097586 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2539148" @default.
- W2012097586 hasPublicationYear "1989" @default.
- W2012097586 type Work @default.
- W2012097586 sameAs 2012097586 @default.
- W2012097586 citedByCount "6" @default.
- W2012097586 crossrefType "journal-article" @default.
- W2012097586 hasAuthorship W2012097586A5004654808 @default.
- W2012097586 hasAuthorship W2012097586A5022360724 @default.
- W2012097586 hasAuthorship W2012097586A5036382303 @default.
- W2012097586 hasAuthorship W2012097586A5073116324 @default.
- W2012097586 hasAuthorship W2012097586A5073519148 @default.
- W2012097586 hasConcept C104317684 @default.
- W2012097586 hasConcept C112446052 @default.
- W2012097586 hasConcept C133307689 @default.
- W2012097586 hasConcept C134018914 @default.
- W2012097586 hasConcept C138626823 @default.
- W2012097586 hasConcept C153911025 @default.
- W2012097586 hasConcept C170493617 @default.
- W2012097586 hasConcept C2777391703 @default.
- W2012097586 hasConcept C2779306644 @default.
- W2012097586 hasConcept C54355233 @default.
- W2012097586 hasConcept C84597430 @default.
- W2012097586 hasConcept C86803240 @default.
- W2012097586 hasConceptScore W2012097586C104317684 @default.
- W2012097586 hasConceptScore W2012097586C112446052 @default.
- W2012097586 hasConceptScore W2012097586C133307689 @default.
- W2012097586 hasConceptScore W2012097586C134018914 @default.
- W2012097586 hasConceptScore W2012097586C138626823 @default.
- W2012097586 hasConceptScore W2012097586C153911025 @default.
- W2012097586 hasConceptScore W2012097586C170493617 @default.
- W2012097586 hasConceptScore W2012097586C2777391703 @default.
- W2012097586 hasConceptScore W2012097586C2779306644 @default.
- W2012097586 hasConceptScore W2012097586C54355233 @default.
- W2012097586 hasConceptScore W2012097586C84597430 @default.
- W2012097586 hasConceptScore W2012097586C86803240 @default.
- W2012097586 hasIssue "3" @default.
- W2012097586 hasLocation W20120975861 @default.
- W2012097586 hasLocation W20120975862 @default.
- W2012097586 hasOpenAccess W2012097586 @default.
- W2012097586 hasPrimaryLocation W20120975861 @default.
- W2012097586 hasRelatedWork W1997650263 @default.
- W2012097586 hasRelatedWork W2022913024 @default.
- W2012097586 hasRelatedWork W2029312328 @default.
- W2012097586 hasRelatedWork W2061805127 @default.
- W2012097586 hasRelatedWork W2075218359 @default.
- W2012097586 hasRelatedWork W2114963489 @default.
- W2012097586 hasRelatedWork W2122944464 @default.
- W2012097586 hasRelatedWork W2416346348 @default.
- W2012097586 hasRelatedWork W2435813906 @default.
- W2012097586 hasRelatedWork W6229197 @default.
- W2012097586 hasVolume "159" @default.
- W2012097586 isParatext "false" @default.
- W2012097586 isRetracted "false" @default.
- W2012097586 magId "2012097586" @default.
- W2012097586 workType "article" @default.