FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012099404> ?p ?o ?g. }

• W2012099404 endingPage "179" @default.
• W2012099404 startingPage "165" @default.
• W2012099404 abstract "This review summarizes new knowledge on expression of genes and provides insights into approaches for study of conceptus-endometrial interactions in ruminants with emphasis on the peri-implantation stage of pregnancy. Conceptus-endometrial interactions in ruminants are complex and involve carefully orchestrated temporal and spatial alterations in gene expression regulated by hormones from the ovary and conceptus. Progesterone is the hormone of pregnancy and acts on the uterus to stimulate blastocyst survival, growth, and development. Inadequate progesterone levels or a delayed rise in progesterone is associated with pregnancy loss. The mononuclear trophectoderm cells of the elongating blastocyst synthesize and secrete interferon-tau (IFNT), the pregnancy recognition signal. Trophoblast giant binucleate cells begin to differentiate and produce hormones including chorionic somatomammotropin 1 (CSH1 or placental lactogen). A number of genes, induced or stimulated by progesterone, IFNT, and/or CSH1 in a cell-specific manner, are implicated in trophectoderm adhesion to the endometrial luminal epithelium and regulation of conceptus growth and differentiation. Transcriptional profiling experiments are beginning to unravel the complex dynamics of conceptus-endometrial interactions in cattle and sheep. Future experiments should incorporate physiological models of pregnancy loss and be complemented by metabolomic studies of uterine lumen contents to more completely define factors required for blastocyst survival, growth, and implantation. Both reduction and holistic approaches will be important to understand the multifactorial phenomenon of recurrent pregnancy loss and provide a basis for new strategies to improve pregnancy outcome and reproductive efficiency in cattle and other domestic animals." @default.
• W2012099404 created "2016-06-24" @default.
• W2012099404 creator A5024292257 @default.
• W2012099404 creator A5076315257 @default.
• W2012099404 creator A5085251562 @default.
• W2012099404 date "2008-02-01" @default.
• W2012099404 modified "2023-10-12" @default.
• W2012099404 title "Genes involved in conceptus–endometrial interactions in ruminants: insights from reductionism and thoughts on holistic approaches" @default.
• W2012099404 cites W1754782457 @default.
• W2012099404 cites W1972998520 @default.
• W2012099404 cites W1976647192 @default.
• W2012099404 cites W1977331240 @default.
• W2012099404 cites W1981936478 @default.
• W2012099404 cites W1985118047 @default.
• W2012099404 cites W1988714961 @default.
• W2012099404 cites W1990835089 @default.
• W2012099404 cites W1992207960 @default.
• W2012099404 cites W1997045496 @default.
• W2012099404 cites W2004051256 @default.
• W2012099404 cites W2005359040 @default.
• W2012099404 cites W2015553913 @default.
• W2012099404 cites W2019757154 @default.
• W2012099404 cites W2020218620 @default.
• W2012099404 cites W2020515914 @default.
• W2012099404 cites W2025236720 @default.
• W2012099404 cites W2028413221 @default.
• W2012099404 cites W2030647283 @default.
• W2012099404 cites W2031432118 @default.
• W2012099404 cites W2033954946 @default.
• W2012099404 cites W2036366604 @default.
• W2012099404 cites W2036444216 @default.
• W2012099404 cites W2039315315 @default.
• W2012099404 cites W2041876825 @default.
• W2012099404 cites W2042830916 @default.
• W2012099404 cites W2043582769 @default.
• W2012099404 cites W2044249849 @default.
• W2012099404 cites W2045272892 @default.
• W2012099404 cites W2045332550 @default.
• W2012099404 cites W2047581757 @default.
• W2012099404 cites W2047764978 @default.
• W2012099404 cites W2048738551 @default.
• W2012099404 cites W2051208397 @default.
• W2012099404 cites W2056758621 @default.
• W2012099404 cites W2061717044 @default.
• W2012099404 cites W2062538325 @default.
• W2012099404 cites W2069648787 @default.
• W2012099404 cites W2072749722 @default.
• W2012099404 cites W2074003366 @default.
• W2012099404 cites W2078221281 @default.
• W2012099404 cites W2079154858 @default.
• W2012099404 cites W2080397589 @default.
• W2012099404 cites W2080599695 @default.
• W2012099404 cites W2080663383 @default.
• W2012099404 cites W2083874559 @default.
• W2012099404 cites W2086017236 @default.
• W2012099404 cites W2088695582 @default.
• W2012099404 cites W2088918528 @default.
• W2012099404 cites W2090141021 @default.
• W2012099404 cites W2094961579 @default.
• W2012099404 cites W2095360746 @default.
• W2012099404 cites W2096474990 @default.
• W2012099404 cites W2097469040 @default.
• W2012099404 cites W2099098790 @default.
• W2012099404 cites W2100272691 @default.
• W2012099404 cites W2103565638 @default.
• W2012099404 cites W2105442339 @default.
• W2012099404 cites W2106058249 @default.
• W2012099404 cites W2106489135 @default.
• W2012099404 cites W2108364190 @default.
• W2012099404 cites W2110378345 @default.
• W2012099404 cites W2112474561 @default.
• W2012099404 cites W2113486732 @default.
• W2012099404 cites W2113525695 @default.
• W2012099404 cites W2113650514 @default.
• W2012099404 cites W2117674318 @default.
• W2012099404 cites W2117916692 @default.
• W2012099404 cites W2120421622 @default.
• W2012099404 cites W2122441736 @default.
• W2012099404 cites W2125682554 @default.
• W2012099404 cites W2126356181 @default.
• W2012099404 cites W2126364226 @default.
• W2012099404 cites W2133991017 @default.
• W2012099404 cites W2135531862 @default.
• W2012099404 cites W2136035099 @default.
• W2012099404 cites W2136689179 @default.
• W2012099404 cites W2136960342 @default.
• W2012099404 cites W2136990134 @default.
• W2012099404 cites W2137307277 @default.
• W2012099404 cites W2137851741 @default.
• W2012099404 cites W2138142695 @default.
• W2012099404 cites W2138921166 @default.
• W2012099404 cites W2139585568 @default.
• W2012099404 cites W2145806560 @default.
• W2012099404 cites W2145864481 @default.
• W2012099404 cites W2146061022 @default.
• W2012099404 cites W2146689228 @default.
• W2012099404 cites W2147995078 @default.
• W2012099404 cites W2150208430 @default.

• next