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- W2012101554 abstract "We describe a label-free ribobase identification method, which uses ionic current measurement to resolve ribonucleoside monophosphates or diphosphates in α-hemolysin protein nanopores containing amino-cyclodextrin adapters. The accuracy of base identification is further investigated through the use of a guanidino-modified adapter. On the basis of these findings, an exosequencing approach is envisioned in which a processive exoribonuclease (polynucleotide phosphorylase) presents sequentially cleaved ribonucleoside diphosphates to a nanopore." @default.
- W2012101554 created "2016-06-24" @default.
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- W2012101554 date "2013-11-13" @default.
- W2012101554 modified "2023-10-17" @default.
- W2012101554 title "Nanopore-Based Identification of Individual Nucleotides for Direct RNA Sequencing" @default.
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- W2012101554 doi "https://doi.org/10.1021/nl403469r" @default.
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