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- W2012102094 abstract "Rates of transmission of hepatitis B virus (HBV) infection from organ donors with HBV markers to recipients along with reactivation of HBV during immunosuppression following transplantation have fallen significantly with the advent of hepatitis B immune globulin (HBIg) and effective antiviral therapy. Although the availability of potent antiviral agents and HBIg has highly impacted the survival rate of HBV-infected patients after transplantation, the high cost associated with this practice represents a major financial burden. The availability of potent antivirals with high genetic barrier to resistance and minimal side effects have made it possible to recommend an HBIg-free prophylactic regimen in selected patients with low viral burden prior to transplant. Significant developments over the last two decades in the understanding and treatment of HBV infection necessitate a re-appraisal of the guidelines for prophylaxis of HBV infection in solid organ transplant recipients." @default.
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- W2012102094 date "2013-05-24" @default.
- W2012102094 modified "2023-10-18" @default.
- W2012102094 title "Prophylaxis of hepatitis B infection in solid organ transplant recipients" @default.
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- W2012102094 doi "https://doi.org/10.1177/1756283x13487942" @default.
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