FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012103426> ?p ?o ?g. }

• W2012103426 endingPage "1007" @default.
• W2012103426 startingPage "988" @default.
• W2012103426 abstract "Vestibular compensation refers to the behavioral recovery after a unilateral peripheral vestibular lesion. In chickens, posture and balance deficits are present immediately following unilateral vestibular ganglionectomy (UVG). After three days, most operated chickens begin to recover, but severe deficits persist in others. The tangential nucleus is a major avian vestibular nucleus whose principal cells are vestibular reflex projection neurons. From patch-clamp recordings on brain slices, the percentage of spontaneous spike firing principal cells, spike discharge rate, ionic conductances, and spontaneous excitatory postsynaptic currents (sEPSCs) were investigated one and three days after UVG. Already by one day after UVG, sEPSC frequency increased significantly on the lesion side, although no differences were detected in the percentage of spontaneous spike firing cells or discharge rate. In compensated chickens three days after UVG, the percentage of spontaneous spike firing cells increased on the lesion side and the discharge rate increased bilaterally. In uncompensated chickens three days after UVG, principal cells on the lesion side showed increased discharge rate and increased sEPSC frequency, whereas principal cells on the intact side were silent. Typically, silent principal cells exhibited smaller persistent sodium conductances and higher activation thresholds for the fast sodium channel than spiking cells. In addition, silent principal cells on the intact side of uncompensated chickens had larger dendrotoxin-sensitive potassium conductance, with a higher ratio of Kv1.1 surface/cytoplasmic expression. Increased sEPSC frequency in principal cells on the lesion side of uncompensated chickens was accompanied by decreased Kv1.2 immunolabeling of presynaptic terminals on principal cell bodies. Thus, both intrinsic ionic conductances and excitatory synaptic inputs play crucial roles at early stages after lesions. Unlike the principal cells in compensated chickens which showed similar percentages of spontaneous spike firing cells, discharge rates, and sEPSC frequencies bilaterally, principal cells in uncompensated chickens displayed gross asymmetry in these properties bilaterally." @default.
• W2012103426 created "2016-06-24" @default.
• W2012103426 creator A5020596818 @default.
• W2012103426 creator A5038789183 @default.
• W2012103426 creator A5046074328 @default.
• W2012103426 creator A5046114746 @default.
• W2012103426 creator A5046555155 @default.
• W2012103426 creator A5047233265 @default.
• W2012103426 date "2009-07-01" @default.
• W2012103426 modified "2023-10-14" @default.
• W2012103426 title "Adaptation of chicken vestibular nucleus neurons to unilateral vestibular ganglionectomy" @default.
• W2012103426 cites W1540766469 @default.
• W2012103426 cites W1583880086 @default.
• W2012103426 cites W1746647265 @default.
• W2012103426 cites W1780083450 @default.
• W2012103426 cites W1785814073 @default.
• W2012103426 cites W1907147354 @default.
• W2012103426 cites W1966004596 @default.
• W2012103426 cites W1974686327 @default.
• W2012103426 cites W1980902873 @default.
• W2012103426 cites W1983682603 @default.
• W2012103426 cites W1991847343 @default.
• W2012103426 cites W1992437048 @default.
• W2012103426 cites W1992881644 @default.
• W2012103426 cites W1993603776 @default.
• W2012103426 cites W2011721893 @default.
• W2012103426 cites W2014314553 @default.
• W2012103426 cites W2014501805 @default.
• W2012103426 cites W2016199512 @default.
• W2012103426 cites W2017366504 @default.
• W2012103426 cites W2017565220 @default.
• W2012103426 cites W2022705283 @default.
• W2012103426 cites W2023674803 @default.
• W2012103426 cites W2024320179 @default.
• W2012103426 cites W2025230169 @default.
• W2012103426 cites W2026001011 @default.
• W2012103426 cites W2029036884 @default.
• W2012103426 cites W2038088893 @default.
• W2012103426 cites W2038755159 @default.
• W2012103426 cites W2043061432 @default.
• W2012103426 cites W2044308835 @default.
• W2012103426 cites W2047769826 @default.
• W2012103426 cites W2050648616 @default.
• W2012103426 cites W2053877839 @default.
• W2012103426 cites W2064700902 @default.
• W2012103426 cites W2064894324 @default.
• W2012103426 cites W2065456289 @default.
• W2012103426 cites W2073764697 @default.
• W2012103426 cites W2074675235 @default.
• W2012103426 cites W2079173805 @default.
• W2012103426 cites W2083882747 @default.
• W2012103426 cites W2084440722 @default.
• W2012103426 cites W2085957678 @default.
• W2012103426 cites W2087927402 @default.
• W2012103426 cites W2092091235 @default.
• W2012103426 cites W2093886032 @default.
• W2012103426 cites W2102101257 @default.
• W2012103426 cites W2106201037 @default.
• W2012103426 cites W2114030821 @default.
• W2012103426 cites W2116241815 @default.
• W2012103426 cites W2120070895 @default.
• W2012103426 cites W2121466553 @default.
• W2012103426 cites W2123588214 @default.
• W2012103426 cites W2142360679 @default.
• W2012103426 cites W2145515501 @default.
• W2012103426 cites W2145628385 @default.
• W2012103426 cites W2168375170 @default.
• W2012103426 cites W2401964813 @default.
• W2012103426 cites W2408608728 @default.
• W2012103426 cites W2418942417 @default.
• W2012103426 cites W3184881181 @default.
• W2012103426 doi "https://doi.org/10.1016/j.neuroscience.2009.04.027" @default.
• W2012103426 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19375485" @default.
• W2012103426 hasPublicationYear "2009" @default.
• W2012103426 type Work @default.
• W2012103426 sameAs 2012103426 @default.
• W2012103426 citedByCount "17" @default.
• W2012103426 countsByYear W20121034262012 @default.
• W2012103426 countsByYear W20121034262014 @default.
• W2012103426 countsByYear W20121034262015 @default.
• W2012103426 countsByYear W20121034262017 @default.
• W2012103426 countsByYear W20121034262018 @default.
• W2012103426 countsByYear W20121034262021 @default.
• W2012103426 countsByYear W20121034262022 @default.
• W2012103426 crossrefType "journal-article" @default.
• W2012103426 hasAuthorship W2012103426A5020596818 @default.
• W2012103426 hasAuthorship W2012103426A5038789183 @default.
• W2012103426 hasAuthorship W2012103426A5046074328 @default.
• W2012103426 hasAuthorship W2012103426A5046114746 @default.
• W2012103426 hasAuthorship W2012103426A5046555155 @default.
• W2012103426 hasAuthorship W2012103426A5047233265 @default.
• W2012103426 hasConcept C105702510 @default.
• W2012103426 hasConcept C112592302 @default.
• W2012103426 hasConcept C134018914 @default.
• W2012103426 hasConcept C142724271 @default.
• W2012103426 hasConcept C169760540 @default.
• W2012103426 hasConcept C17077164 @default.
• W2012103426 hasConcept C185592680 @default.

• next