FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012105296> ?p ?o ?g. }

• W2012105296 endingPage "5048" @default.
• W2012105296 startingPage "5041" @default.
• W2012105296 abstract "The uptake of ganglioside analogues by a permanent mouse fibroblast cell line has been studied by radio-tracer techniques and ESR spectroscopy with 3H- and nitroxide-labeled compounds. Analogues of GM1, GM2, and GM3 monosialogangliosides and of GD1a and GD3 disialogangliosides were synthesized. The spin-label group was situated on the 5-, 9-, or 13-carbon atom of the C18 fatty acid chain, and the 3H label was in the carbohydrate moiety. Part of the ganglioside associated with the cells could be removed by trypsin treatment and was shown to consist of ganglioside micelles attached to the cell surface. The trypsin-resistant component displayed characteristic anisotropic ESR spectra which closely resembled those of the same spin-labeled analogues at low dilution in liposomes prepared from the extracted cell lipids. The flexibility gradient, polarity profile, and temperature dependence displayed by the spectra were similar to those found for fluid phospholipid bilayer model membranes, and the high effective order parameters suggested a location in the cell plasma membrane. Similar results were obtained for all the different ganglioside analogues, indicating a common anchoring region in the hydrophobic interior of the membrane. Under the incubation conditions used the amount of trypsin-resistant ganglioside analogue taken up by the cells was about 15 nmol/mg of cellular protein, irrespective of the nature of the oligosaccharide moiety. By use of the natural ganglioside [3H]GM3, the trypsin-resistant uptake was about 19 nmol/mg of cellular protein. Although these amounts are quite similar, the uptake kinetics differed between the true ganglioside GM3 and the ganglioside analogues." @default.
• W2012105296 created "2016-06-24" @default.
• W2012105296 creator A5007309669 @default.
• W2012105296 creator A5046402579 @default.
• W2012105296 creator A5062821743 @default.
• W2012105296 creator A5072065214 @default.
• W2012105296 creator A5078862100 @default.
• W2012105296 date "1983-10-11" @default.
• W2012105296 modified "2023-09-27" @default.
• W2012105296 title "Incorporation of ganglioside analogs into fibroblast cell membranes. A spin-label study" @default.
• W2012105296 cites W1536299500 @default.
• W2012105296 cites W1775749144 @default.
• W2012105296 cites W1974732548 @default.
• W2012105296 cites W2000527155 @default.
• W2012105296 cites W2006924060 @default.
• W2012105296 cites W2009949150 @default.
• W2012105296 cites W2055499537 @default.
• W2012105296 cites W2058962424 @default.
• W2012105296 cites W2064048353 @default.
• W2012105296 cites W2078453327 @default.
• W2012105296 cites W2088049062 @default.
• W2012105296 cites W2092785091 @default.
• W2012105296 cites W2095549072 @default.
• W2012105296 cites W2101282728 @default.
• W2012105296 cites W2129468828 @default.
• W2012105296 cites W2132825518 @default.
• W2012105296 cites W2168526937 @default.
• W2012105296 cites W2314590516 @default.
• W2012105296 cites W2320646336 @default.
• W2012105296 cites W2326448744 @default.
• W2012105296 cites W2345558803 @default.
• W2012105296 cites W562290930 @default.
• W2012105296 cites W2416605330 @default.
• W2012105296 doi "https://doi.org/10.1021/bi00290a025" @default.
• W2012105296 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6315058" @default.
• W2012105296 hasPublicationYear "1983" @default.
• W2012105296 type Work @default.
• W2012105296 sameAs 2012105296 @default.
• W2012105296 citedByCount "152" @default.
• W2012105296 countsByYear W20121052962012 @default.
• W2012105296 countsByYear W20121052962013 @default.
• W2012105296 countsByYear W20121052962014 @default.
• W2012105296 countsByYear W20121052962018 @default.
• W2012105296 countsByYear W20121052962020 @default.
• W2012105296 countsByYear W20121052962021 @default.
• W2012105296 countsByYear W20121052962022 @default.
• W2012105296 countsByYear W20121052962023 @default.
• W2012105296 crossrefType "journal-article" @default.
• W2012105296 hasAuthorship W2012105296A5007309669 @default.
• W2012105296 hasAuthorship W2012105296A5046402579 @default.
• W2012105296 hasAuthorship W2012105296A5062821743 @default.
• W2012105296 hasAuthorship W2012105296A5072065214 @default.
• W2012105296 hasAuthorship W2012105296A5078862100 @default.
• W2012105296 hasConcept C177462420 @default.
• W2012105296 hasConcept C181199279 @default.
• W2012105296 hasConcept C185154212 @default.
• W2012105296 hasConcept C185592680 @default.
• W2012105296 hasConcept C192157962 @default.
• W2012105296 hasConcept C202751555 @default.
• W2012105296 hasConcept C2776568683 @default.
• W2012105296 hasConcept C2777331542 @default.
• W2012105296 hasConcept C2777726330 @default.
• W2012105296 hasConcept C2778106830 @default.
• W2012105296 hasConcept C2778918659 @default.
• W2012105296 hasConcept C2780340462 @default.
• W2012105296 hasConcept C2780381497 @default.
• W2012105296 hasConcept C39944091 @default.
• W2012105296 hasConcept C41625074 @default.
• W2012105296 hasConcept C55493867 @default.
• W2012105296 hasConcept C71240020 @default.
• W2012105296 hasConcept C79123411 @default.
• W2012105296 hasConceptScore W2012105296C177462420 @default.
• W2012105296 hasConceptScore W2012105296C181199279 @default.
• W2012105296 hasConceptScore W2012105296C185154212 @default.
• W2012105296 hasConceptScore W2012105296C185592680 @default.
• W2012105296 hasConceptScore W2012105296C192157962 @default.
• W2012105296 hasConceptScore W2012105296C202751555 @default.
• W2012105296 hasConceptScore W2012105296C2776568683 @default.
• W2012105296 hasConceptScore W2012105296C2777331542 @default.
• W2012105296 hasConceptScore W2012105296C2777726330 @default.
• W2012105296 hasConceptScore W2012105296C2778106830 @default.
• W2012105296 hasConceptScore W2012105296C2778918659 @default.
• W2012105296 hasConceptScore W2012105296C2780340462 @default.
• W2012105296 hasConceptScore W2012105296C2780381497 @default.
• W2012105296 hasConceptScore W2012105296C39944091 @default.
• W2012105296 hasConceptScore W2012105296C41625074 @default.
• W2012105296 hasConceptScore W2012105296C55493867 @default.
• W2012105296 hasConceptScore W2012105296C71240020 @default.
• W2012105296 hasConceptScore W2012105296C79123411 @default.
• W2012105296 hasIssue "21" @default.
• W2012105296 hasLocation W20121052961 @default.
• W2012105296 hasLocation W20121052962 @default.
• W2012105296 hasOpenAccess W2012105296 @default.
• W2012105296 hasPrimaryLocation W20121052961 @default.
• W2012105296 hasRelatedWork W124525801 @default.
• W2012105296 hasRelatedWork W163652335 @default.
• W2012105296 hasRelatedWork W1994071682 @default.
• W2012105296 hasRelatedWork W2012105296 @default.

• next