FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012107934> ?p ?o ?g. }

• W2012107934 endingPage "723" @default.
• W2012107934 startingPage "715" @default.
• W2012107934 abstract "We sought to assess the effect of anticoagulation control on long-term survival after valve replacement with the Medtronic Hall valve (Medtronic, Inc, Minneapolis, Minn).Prospective follow-up data, including 82,297 international normalized ratios, were collected for 1476 patients undergoing single valve replacement with the Medtronic Hall valve between 1979 and 1994, with follow-up to the end of 1998. After excluding 204 patients who either died within 30 days or had fewer than 10 international normalized ratios recorded beyond 30 days, there were 10,203 patient years of follow-up for analysis. Anticoagulation variability was measured as the percentage of international normalized ratios outside a target range of 2.0 to 4.0 for each patient.Linearized rates for late death rose progressively with increasing deciles of anticoagulation variability for both aortic and mitral valve replacement (2.7% and 3.3% per year, respectively, in deciles 1 and 2 up to 9.5% and 14.6% per year, respectively, in deciles 6-10; P <.001). Survival at 15 years after aortic valve replacement was 59% for low anticoagulation variability (deciles 1 and 2), 55% for intermediate anticoagulation variability (decile 3), and 28% for high anticoagulation variability (deciles 4-10); survivals at 15 years after mitral valve replacement were 56%, 42%, and 24%, respectively (P <.001 between low-intermediate anticoagulation variability and high anticoagulation variability for both aortic and mitral valve replacement). On multivariate analysis, significant predictors of reduced survival were anticoagulation variability per 20% increase (hazard ratio, 1.8), diabetes (hazard ratio, 1.6), decade of age (hazard ratio, 1.6), concomitant coronary artery bypass grafting (hazard ratio, 1.5), male sex (hazard ratio, 1.4), hypertension (hazard ratio, 1.4), New York Heart Association class III or IV (hazard ratio, 1.3), and non-sinus rhythm (hazard ratio, 1.2). Patients with low anticoagulation variability who were in sinus rhythm and did not have diabetes, coronary bypass grafting, or hypertension had survivals equal to those of the age- and sex-matched general population at 15 years. The incidence of valve-related deaths was significantly higher with high anticoagulation variability compared with the incidence with low-intermediate anticoagulation variability for both aortic (1.4% vs 0.5% per year, P <.001) and mitral valve replacement (1.5% vs 0.5% per year, P <.001). By means of univariate analysis, high anticoagulation variability was significantly associated with New York Heart Association class III or IV at 5 years postoperatively (P <.001) and with age of greater than 60 years at the time of the operation (P =.002).High anticoagulation variability is the most important independent predictor of reduced survival after valve replacement with a mechanical valve. Better anticoagulation control should improve survival." @default.
• W2012107934 created "2016-06-24" @default.
• W2012107934 creator A5029724425 @default.
• W2012107934 creator A5031524039 @default.
• W2012107934 creator A5053841905 @default.
• W2012107934 creator A5057294468 @default.
• W2012107934 creator A5078099029 @default.
• W2012107934 creator A5086908612 @default.
• W2012107934 date "2002-04-01" @default.
• W2012107934 modified "2023-10-17" @default.
• W2012107934 title "Better anticoagulation control improves survival after valve replacement" @default.
• W2012107934 cites W1603870906 @default.
• W2012107934 cites W166667800 @default.
• W2012107934 cites W1785968800 @default.
• W2012107934 cites W1968018886 @default.
• W2012107934 cites W1972435865 @default.
• W2012107934 cites W1978193003 @default.
• W2012107934 cites W1992147175 @default.
• W2012107934 cites W1996007106 @default.
• W2012107934 cites W1999297045 @default.
• W2012107934 cites W2008635765 @default.
• W2012107934 cites W2012923240 @default.
• W2012107934 cites W2013340250 @default.
• W2012107934 cites W2019452952 @default.
• W2012107934 cites W2026783020 @default.
• W2012107934 cites W2032892632 @default.
• W2012107934 cites W2035218180 @default.
• W2012107934 cites W2035872736 @default.
• W2012107934 cites W2043660630 @default.
• W2012107934 cites W2055771484 @default.
• W2012107934 cites W2057484890 @default.
• W2012107934 cites W2074577477 @default.
• W2012107934 cites W2082378560 @default.
• W2012107934 cites W2101344036 @default.
• W2012107934 cites W2101836903 @default.
• W2012107934 cites W2129574541 @default.
• W2012107934 cites W2149466695 @default.
• W2012107934 cites W2170931442 @default.
• W2012107934 cites W2462438782 @default.
• W2012107934 cites W2613716153 @default.
• W2012107934 cites W4293241248 @default.
• W2012107934 doi "https://doi.org/10.1067/mtc.2002.121162" @default.
• W2012107934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11986600" @default.
• W2012107934 hasPublicationYear "2002" @default.
• W2012107934 type Work @default.
• W2012107934 sameAs 2012107934 @default.
• W2012107934 citedByCount "136" @default.
• W2012107934 countsByYear W20121079342012 @default.
• W2012107934 countsByYear W20121079342013 @default.
• W2012107934 countsByYear W20121079342014 @default.
• W2012107934 countsByYear W20121079342015 @default.
• W2012107934 countsByYear W20121079342016 @default.
• W2012107934 countsByYear W20121079342017 @default.
• W2012107934 countsByYear W20121079342018 @default.
• W2012107934 countsByYear W20121079342019 @default.
• W2012107934 countsByYear W20121079342020 @default.
• W2012107934 countsByYear W20121079342021 @default.
• W2012107934 countsByYear W20121079342023 @default.
• W2012107934 crossrefType "journal-article" @default.
• W2012107934 hasAuthorship W2012107934A5029724425 @default.
• W2012107934 hasAuthorship W2012107934A5031524039 @default.
• W2012107934 hasAuthorship W2012107934A5053841905 @default.
• W2012107934 hasAuthorship W2012107934A5057294468 @default.
• W2012107934 hasAuthorship W2012107934A5078099029 @default.
• W2012107934 hasAuthorship W2012107934A5086908612 @default.
• W2012107934 hasBestOaLocation W20121079341 @default.
• W2012107934 hasConcept C105795698 @default.
• W2012107934 hasConcept C126322002 @default.
• W2012107934 hasConcept C141071460 @default.
• W2012107934 hasConcept C147021879 @default.
• W2012107934 hasConcept C164705383 @default.
• W2012107934 hasConcept C207103383 @default.
• W2012107934 hasConcept C2775854548 @default.
• W2012107934 hasConcept C2776570981 @default.
• W2012107934 hasConcept C2777543888 @default.
• W2012107934 hasConcept C2780007028 @default.
• W2012107934 hasConcept C2780026749 @default.
• W2012107934 hasConcept C33923547 @default.
• W2012107934 hasConcept C44249647 @default.
• W2012107934 hasConcept C50382708 @default.
• W2012107934 hasConcept C71924100 @default.
• W2012107934 hasConceptScore W2012107934C105795698 @default.
• W2012107934 hasConceptScore W2012107934C126322002 @default.
• W2012107934 hasConceptScore W2012107934C141071460 @default.
• W2012107934 hasConceptScore W2012107934C147021879 @default.
• W2012107934 hasConceptScore W2012107934C164705383 @default.
• W2012107934 hasConceptScore W2012107934C207103383 @default.
• W2012107934 hasConceptScore W2012107934C2775854548 @default.
• W2012107934 hasConceptScore W2012107934C2776570981 @default.
• W2012107934 hasConceptScore W2012107934C2777543888 @default.
• W2012107934 hasConceptScore W2012107934C2780007028 @default.
• W2012107934 hasConceptScore W2012107934C2780026749 @default.
• W2012107934 hasConceptScore W2012107934C33923547 @default.
• W2012107934 hasConceptScore W2012107934C44249647 @default.
• W2012107934 hasConceptScore W2012107934C50382708 @default.
• W2012107934 hasConceptScore W2012107934C71924100 @default.
• W2012107934 hasIssue "4" @default.
• W2012107934 hasLocation W20121079341 @default.

• next