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• W2012110689 abstract "Purpose/Objective(s)Ultrasound (US)-CT modality can be used to provide accurate target definition for prostate IMRT planning. However, several physical uncertainties which may impact the accuracy of this modality, such as the US speeds in different soft tissues and the pressure of US probe on abdomen, have been neglected by current technique. In this study we evaluated the accuracy of US-CT modality for US-guided prostate IMRT planning after systemic correction of these physical uncertainties.Materials/MethodsFive patients were included in this study. A 3-D US-CT scan was performed for all patients. In current US-CT modality, the ultrasound system (RestituTM) was integrated with CT-sim through a camera system which was calibrated to the intersection point of wall lasers of CT-sim. Three steps were adopted sequentially to reduce the uncertainties of US-CT modality. First, three BBs were placed on the patient's skin to compensate for the mechanical inaccuracy of wall lasers of CT-sim. Second, a finite element method was applied to trace the displacement of prostate induced by US probe pressure during US scan. Finally, CT images were used to distinguish soft tissues which corresponded to different US propagation speed. The three-dimensional vector displacement of prostate obtained from these three steps was corrected by iso-center shift in US-CT match. A physician contoured the treatment targets and surrounding critical organs on CT images. The prostate was then contoured on US images for comparison. The accuracy of such correction was evaluated by the overlapping volume ratio (OVR), which is the ratio of the overlapped prostate volume between US and CT over the prostate volume on US images.ResultsFor all the patients, the US probe-induce abdominal skin deformation and fat thickness ranged from 2 cm to 4.7 cm and from 1.7 cm to 5.2 cm, respectively. The volume of the prostate drawn on US images is 24%–44% less than that obtained from CT images. Compared to the US-CT match without correction, the proposed method increased OVR value from 0.796 ± 0.189 to 0.972 ± 0.041 (Table).ConclusionsTabled 1Quantitative evaluation of the accuracy of US-CT match for five patientsPatientFat depth (cm)Probe (cm)Correction (mm)CT volume (cc)US volume (cc)OVR before correctionOVR after correction13.54.75.033.423.80.500.9123.84.45.025.219.10.751.0035.22.03.625.714.30.831.0043.23.13.119.411.91.001.0051.72.01.871.547.70.900.95 Open table in a new tab Purpose/Objective(s)Ultrasound (US)-CT modality can be used to provide accurate target definition for prostate IMRT planning. However, several physical uncertainties which may impact the accuracy of this modality, such as the US speeds in different soft tissues and the pressure of US probe on abdomen, have been neglected by current technique. In this study we evaluated the accuracy of US-CT modality for US-guided prostate IMRT planning after systemic correction of these physical uncertainties. Ultrasound (US)-CT modality can be used to provide accurate target definition for prostate IMRT planning. However, several physical uncertainties which may impact the accuracy of this modality, such as the US speeds in different soft tissues and the pressure of US probe on abdomen, have been neglected by current technique. In this study we evaluated the accuracy of US-CT modality for US-guided prostate IMRT planning after systemic correction of these physical uncertainties. Materials/MethodsFive patients were included in this study. A 3-D US-CT scan was performed for all patients. In current US-CT modality, the ultrasound system (RestituTM) was integrated with CT-sim through a camera system which was calibrated to the intersection point of wall lasers of CT-sim. Three steps were adopted sequentially to reduce the uncertainties of US-CT modality. First, three BBs were placed on the patient's skin to compensate for the mechanical inaccuracy of wall lasers of CT-sim. Second, a finite element method was applied to trace the displacement of prostate induced by US probe pressure during US scan. Finally, CT images were used to distinguish soft tissues which corresponded to different US propagation speed. The three-dimensional vector displacement of prostate obtained from these three steps was corrected by iso-center shift in US-CT match. A physician contoured the treatment targets and surrounding critical organs on CT images. The prostate was then contoured on US images for comparison. The accuracy of such correction was evaluated by the overlapping volume ratio (OVR), which is the ratio of the overlapped prostate volume between US and CT over the prostate volume on US images. Five patients were included in this study. A 3-D US-CT scan was performed for all patients. In current US-CT modality, the ultrasound system (RestituTM) was integrated with CT-sim through a camera system which was calibrated to the intersection point of wall lasers of CT-sim. Three steps were adopted sequentially to reduce the uncertainties of US-CT modality. First, three BBs were placed on the patient's skin to compensate for the mechanical inaccuracy of wall lasers of CT-sim. Second, a finite element method was applied to trace the displacement of prostate induced by US probe pressure during US scan. Finally, CT images were used to distinguish soft tissues which corresponded to different US propagation speed. The three-dimensional vector displacement of prostate obtained from these three steps was corrected by iso-center shift in US-CT match. A physician contoured the treatment targets and surrounding critical organs on CT images. The prostate was then contoured on US images for comparison. The accuracy of such correction was evaluated by the overlapping volume ratio (OVR), which is the ratio of the overlapped prostate volume between US and CT over the prostate volume on US images. ResultsFor all the patients, the US probe-induce abdominal skin deformation and fat thickness ranged from 2 cm to 4.7 cm and from 1.7 cm to 5.2 cm, respectively. The volume of the prostate drawn on US images is 24%–44% less than that obtained from CT images. Compared to the US-CT match without correction, the proposed method increased OVR value from 0.796 ± 0.189 to 0.972 ± 0.041 (Table). For all the patients, the US probe-induce abdominal skin deformation and fat thickness ranged from 2 cm to 4.7 cm and from 1.7 cm to 5.2 cm, respectively. The volume of the prostate drawn on US images is 24%–44% less than that obtained from CT images. Compared to the US-CT match without correction, the proposed method increased OVR value from 0.796 ± 0.189 to 0.972 ± 0.041 (Table). ConclusionsTabled 1Quantitative evaluation of the accuracy of US-CT match for five patientsPatientFat depth (cm)Probe (cm)Correction (mm)CT volume (cc)US volume (cc)OVR before correctionOVR after correction13.54.75.033.423.80.500.9123.84.45.025.219.10.751.0035.22.03.625.714.30.831.0043.23.13.119.411.91.001.0051.72.01.871.547.70.900.95 Open table in a new tab" @default.
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• W2012110689 title "An Investigation of the Accuracy of Ultrasound-CT Modality for Ultrasound Guided Prostate IMRT Planning" @default.
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