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• W2012113365 abstract "Mitotic kinesin spindle protein (KSP) is involved in the assembly of the bipolar spindle during cell division. On the basis of a common 2,3-fused indole substructure within the complex frameworks of terpendole E and other KSP inhibitors, the carbazoles with a bulky alkyl group were identified as a novel KSP inhibitory scaffold. Additionally, among several naturally occurring cell growth inhibitors with 2,3-fused indole structures, beta-carboline alkaloids, harman and harmine, showed moderate inhibition of KSP." @default.
• W2012113365 created "2016-06-24" @default.
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• W2012113365 date "2010-06-03" @default.
• W2012113365 modified "2023-10-16" @default.
• W2012113365 title "Kinesin Spindle Protein (KSP) Inhibitors with 2,3-Fused Indole Scaffolds" @default.
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• W2012113365 doi "https://doi.org/10.1021/jm100476d" @default.
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